Shimizu Saki

シミズサキ | Shimizu Saki

Affiliation and department：
Job title： Associate Professor

Research field (1)： Pharmacology

Research keywords (7)：統合失調症 , うつ・不安 , パーキンソン病 , 錐体外路障害 , 振戦 , アストロサイト , Kir4.1チャネル

Research theme for competitive and other funds (4)：

2021 - 2024 Analysis of the mechanisms underlying development of neuropsychiatric diseases with focus on astrocytic potassium buffering function
2019 - 2022 過分極作動性HCN1チャネルを介したてんかん発症の調節メカニズム解析
2016 - 2019 本態性振戦の病態メカニズム解析と新たな治療薬ターゲットの解明
2014 - 2017 シナプス分泌機構に着目したてんかん病態解析

Papers (46)：

Masato Kinboshi, Saki Shimizu, Kentaro Tokudome, Tomoji Mashimo, Tadao Serikawa, Hidefumi Ito, Ryosuke Takahashi, Akio Ikeda, Yukihiro Ohno. Imbalance of glutamatergic and GABAergic neurotransmission in audiogenic seizure-susceptible Leucine-rich glioma-inactivated 1 (Lgi1)-mutant rats. Heliyon. 2023. 9. 7. e17984-e17984
Masaki Kato, Naofumi Kunisawa, Saki Shimizu, Higor A. Iha, Yukihiro Ohno. Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor. Frontiers in Pharmacology. 2022. 13
Yukihiro Ohno, Naofumi Kunisawa, Saki Shimizu. Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases. International Journal of Molecular Sciences. 2021. 22. 19. 10236-10236
Ai Nishitani, Haruna Nagayoshi, Shigeo Takenaka, Masahide Asano, Saki Shimizu, Yukihiro Ohno, Takashi Kuramoto. Involvement of NMDA receptors in tremor expression in Aspa/Hcn1 double-knockout rats. Experimental animals. 2020. 69. 4. 388-394
Tadao Serikawa, Naofumi Kunisawa, Saki Shimizu, Masaki Kato, Higor Alves Iha, Masato Kinboshi, Hisao Nishikawa, Yu Shirakawa, Birger Voigt, Satoshi Nakanishi, et al. Increased seizure sensitivity, emotional defects and cognitive impairment in PHD finger protein 24 (Phf24)-null rats. Behavioural brain research. 2019. 369. 111922-111922

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MISC (11)：

清水佐紀, 大野行弘. 抗発作薬の作用機序-Mechanism of action of anti-seizure agents-特集てんかん診療update. 日本臨床 = Japanese journal of clinical medicine. 2022. 80. 12. 1883-1887
國澤直史, 久積博明, 加藤将貴, 清水佐紀, 佐藤和明, 金星匡人, 松橋眞生, 池田昭夫, 芹川忠夫, 大野行弘. Wide-band EEG analysis during PTZ-induced seizure in Phf24-KO rats. 日本薬学会年会要旨集(Web). 2021. 141st
久積博明, 佐藤和明, 佐藤和明, 國澤直史, 金星匡人, 金星匡人, 松橋眞生, 池田昭夫, 清水佐紀, 大野行弘. Wide-band EEG measurements in pilocarpine-induced epilepsy model rats. 日本薬学会年会要旨集(Web). 2020. 140th
清水佐紀. Prediction and management of antipsychotic drug-induced extrapyramidal side effects based on serotonergic regulatory mechanisms. 大阪薬科大学紀要(Web). 2019. 13. 135-144 (WEB ONLY)
大野行弘, 加藤将貴, 清水佐紀. 喫煙のサイエンス III 基礎医学とのダイアローグニコチン性アセチルコリン受容体(ニコチン受容体)と作用薬. Lung Perspectives. 2019. 27. 1. 62-66

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Books (4)：

In Vivo Neuropharmacology and Neurophysiology
Springer 2017
Emerging Drugs and Targets for Parkinson’s Disease
RSC Publishing 2013
Antipsychotic Drugs: Pharmacology, Side Effects and Abuse Prevention
Nova Science Publishers 2013
Schizophrenia Research: Recent Advances
Nova Science Publishers 2012

Professional career (1)：

博士(薬科学)

Association Membership(s) (5)：

THE JAPANESE PHARMACOLOGICAL SOCIETY , THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE SOCIETY OF TOXICOLOGY

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