Nozaki Tomoyoshi

ノザキトモヨシ | Nozaki Tomoyoshi

Affiliation and department：

Research field (1)： Parasitology

Research theme for competitive and other funds (37)：

2021 - 2025 A study for the construction and application of Jomon iPS cells
2021 - 2024 生体機能チップを用いた腸管感染症における病原体-ヒト相互作用の解明
2021 - 2024 赤痢アメーバの病原機構における脂質輸送タンパク質の機能解明
2021 - 2023 原虫核からヒト細胞核へ移行する新規宿主制御因子の解明
2019 - 2022 Phoshatidylinositol signal in the enteric protozoan parasite Entamoeba histolytica

2018 - 2021 Analysis of molecular mechanism of trogocytosis in Entamoeba histolytica

2017 - 2019 Analysis of novel mitochondrion-related organelles in Entamoeba histolytica

2016 - 2017 マトリョーシカ型進化原理の展開

2014 - 2017 Elucidation of molecular mechanisms of protease secretion in Entamoeba histolytica

2014 - 2016 赤痢アメーバ病原性を制御するフォスファチジルイノシトールリン酸シグナリングの解明

2011 - 2016 Multidirectional evolution of mitochondria

2011 - 2016 Matryoshka-type evolution

2011 - 2016 "Matryoshka"-type evolution of eukaryotes

2011 - 2014 Molecular Basis of differentiation of Entamoeba histolytica

2006 - 2011 Matrix of Infection Phenomena

2008 - 2010 The genomic epidemiology and immunological cohort study on amoebiasis in South Asia

2008 - 2010 Molecular Basis of Transport of Virulence Factors in the Pathogenic Protist

2006 - 2010 Diversity of energy transducing mechanism by organella from the parasites such as Plasmodium

2006 - 2010 Role of sulfur-containing amino acid metabolism in protozoan infections

2006 - 2007 感染における病原体内トラフィックの解明

2005 - 2006 Comprehensive understanding of the virulence mechanisms of Entamoeba histolytica

2004 - 2005 寄生性原虫の病原機構におけるメンブレントラフィックの役割

2004 - 2005 赤痢アメーバにおける鉄硫黄タンパク質の生合成機構の解明

2004 - 2005 Biosyrdiesis of iron-sulfur proteins in Enlanoeba histotyrica

2003 - 2004 Anaysis of vesicular trafficking in Entamoeba histolytica

2003 - 2003 原虫における鉄硫黄タンパク質の生合成機構の解明

2001 - 2003 THE DEVELOPMENT OF NEW DAIAGNOSTICS AND CHEMOTHERAPEUTICS AGAINST ECHINOCOCCAL INFECTION

2002 - 2002 原虫における鉄硫黄タンパク質の生合成機構の解明

2001 - 2002 A basic research on anti-oxidant system of Plasmodium falciparum for its suitability as targets for anti-malarial chemotherapy: In special relation to the parasite peroxiredoxins as the drug targets.

1999 - 2000 赤痢アメーバにおけるシステイン合成経路の解析

1998 - 2000 Study for NTPase from the newly recognized parasitic protozoan Neospora caninum

1999 - 1999 マラリア原虫における特異的システイン生合成経路の解析:薬剤及びワクチン開発の標的として

1997 - 1999 Cell Biological, Epidemiological and Clinical Studies on Entamoeba dispar infection

1997 - 1998 病原性トリパノソーマのヌクレアーゼの機能解析に関する研究

1997 - 1997 STUDY OF CONGENITAL CHAGAS' DISEASE

1996 - 1997 Establishment of axnic culture of non-invasive Entamoeba dispar and study on its biological characterization

1996 - 1996 マラリア原虫のクロロキン耐性を消去する薬剤の開発と作用機構に関する研究

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Papers (209)：

Akira Ebihara, Raimu Taguchi, Ghulam Jeelani, Tomoyoshi Nozaki, Kiyotake Suenaga, Arihiro Iwasaki. Kagimminols A and B, Cembrene-Type Diterpenes from an Okeania sp. Marine Cyanobacterium. Journal of natural products. 2024
Kairi Umeda, Arihiro Iwasaki, Raimu Taguchi, Naoaki Kurisawa, Ghulam Jeelani, Tomoyoshi Nozaki, Kiyotake Suenaga. Isolation and Structure Determination of Akunolides, Macrolide Glycosides from a Marine Okeania sp. Cyanobacterium. Journal of natural products. 2023. 86. 11. 2529-2538
Sanjib K Sardar, Ajanta Ghosal, Tapas Haldar, Koushik Das, Yumiko Saito-Nakano, Seiki Kobayashi, Shanta Dutta, Tomoyoshi Nozaki, Sandipan Ganguly. Investigating genetic polymorphism in E. histolytica isolates with distinct clinical phenotypes. Parasitology research. 2023. 122. 11. 2525-2537
Ajanta Ghosal, Sanjib K Sardar, Tapas Haldar, Maimoon Maruf, Yumiko Saito-Nakano, Shanta Dutta, Tomoyoshi Nozaki, Sandipan Ganguly. Genotyping and epidemiological distribution of diarrhea-causing isolates of Giardia duodenalis in southeastern part of West Bengal, India. Parasitology research. 2023. 122. 11. 2567-2584
Natsuki Watanabe, Yumiko Saito-Nakano, Naoaki Kurisawa, Keisuke Otomo, Kiyotake Suenaga, Kentaro Nakano, Tomoyoshi Nozaki. Fumagillin inhibits growth of the enteric protozoan parasite Entamoeba histolytica by covalently binding to and selectively inhibiting methionine aminopeptidase 2. Antimicrobial agents and chemotherapy. 2023. e0056023

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MISC (35)：

花舘有希, 花舘有希, 津久井久美子, 野崎智義, 中野由美子. 腸管寄生性原虫赤痢アメーバにおけるEhRab8A GTPase結合タンパク質EhCdc50の同定. 日本寄生虫学会大会プログラム・抄録集. 2019. 88th
F. Takeuchi, Y. Ogasawara, K. Kato, T. Sekizuka, T. Nozaki, Y. Sugita-Konishi, T. Ohnishi, M. Kuroda. Genetic variants of Kudoa septempunctata (Myxozoa: Multivalvulida), a flounder parasite causing foodborne disease (vol 39, pg 667, 2016). JOURNAL OF FISH DISEASES. 2017. 40. 12. 1941-1941
Yasuaki Yanagawa, Koji Watanabe, Naoyoshi Nagata, Kumiko Tsukui, Seiki Kobayashi, Tomoyoshi Nozaki, Hiroyuki Gatanaga, Yoshimi Kikuchi, Shinichi Oka. DIAGNOSTIC ACCURACY OF AMEBIC COLITIS BY COLONOSCOPY. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2017. 95. 5. 172-172
森美穂子, 森美穂子, 深澤航, 伯耆原愛, 柘植聡志, 野中健一, 野中健一, 松本厚子, 松本厚子, 大村智, et al. 微生物二次代謝産物からの赤痢アメーバ特異的システイン合成酵素阻害化合物の探索. 日本農芸化学会大会講演要旨集(Web). 2016. 2016
柘植聡志, 深澤航, 森美穂子, 森美穂子, 野中健一, 野中健一, 松本厚子, 松本厚子, 野崎智義, 大村智, et al. 微生物代謝産物からの抗赤痢アメーバ物質の探索. 日本農芸化学会大会講演要旨集(Web). 2016. 2016

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Books (5)：

Oxidative Stress in Microbial Diseases
Springer Nature Singapore Pte Ltd. 2019
Echinococcosis
2017 ISBN:9789535135913
Amebiasis : biology and pathogenesis of entamoeba
Springer 2015 ISBN:9784431551997
Amebiasis: Biology and Pathogenesis of Entamoeba
Springer 2015 ISBN:9784431551997
Amebiasis: Biology and Pathogenesis of Entamoeba
Springer 2015 ISBN:9784431551997

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