Rchr
J-GLOBAL ID:201901005675189053   Update date: Feb. 01, 2024

Koike Atsushi

コイケ アツシ | Koike Atsushi
Affiliation and department:
Research field  (1): Pharmaceuticals - health and biochemistry
Research keywords  (4): Tumor Immunity ,  Inflammatory ,  Innate immunity ,  macrophages
Research theme for competitive and other funds  (5):
  • 2022 - 2025 ゲラニルゲラニル転移酵素による肺線維化の制御機構の解明
  • 2020 - 2023 Regulation mechanism of obesity by eicosanoids
  • 2022 - 2023 きのこ由来の転位型ステロイド化合物による抗腫瘍作用と腫瘍免疫活性化能に関する研究
  • 2017 - 2020 TLRシグナルを介した新奇薬物相互作用によるマクロファージ細胞死の分子機構の解明
  • 2014 - 2016 天然物からの活性化マクロファージ特異的に作用する制御物質の探索と作用機構の解明
Papers (21):
  • Jun Yee Tse, Atsushi Koike, Kazunori Kadota, Hiromasa Uchiyama, Ko Fujimori, Yuichi Tozuka. Porous particles and novel carrier particles with enhanced penetration for efficient pulmonary delivery of antitubercular drugs. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2021. 167. 116-126
  • Mayuko Sugimoto, Risa Ko, Hiromi Goshima, Atsushi Koike, Makio Shibano, Ko Fujimori. Formononetin attenuates H2O2-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cells. Neurotoxicology. 2021. 85. 186-200
  • Atsushi Koike, Kaito Tsujinaka, Ko Fujimori. Statins attenuate antiviral IFN-β and ISG expression via inhibition of IRF3 and JAK/STAT signaling in poly(I:C)-treated hyperlipidemic mice and macrophages. The FEBS journal. 2021
  • Atsushi Koike. Molecular Mechanism Underlying Inflammatory Cell Death via Necroptosis in M1 Macrophages. YAKUGAKU ZASSHI. 2020. 140. 12. 1427-1432
  • Tomoya Kawakami, Atsushi Koike, Toko Maehara, Tetsuya Hayashi, Ko Fujimori. Bicarbonate enhances the inflammatory response by activating JAK/STAT signalling in LPS + IFN-γ-stimulated macrophages. Journal of biochemistry. 2020. 167. 6. 623-631
more...
MISC (58):
Education (3):
  • 2008 - 2012 Kobe University Graduate School of Medicine
  • 2004 - 2006 Kobe University Graduate School of Medicine
  • 2000 - 2004 Osaka University of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences
Professional career (1):
  • 博士(医学) (神戸大学)
Work history (6):
  • 2021/04 - 現在 大阪医科薬科大学 薬学部 病態生化学研究室 講師
  • 2018/04 - 現在 Osaka University of Pharmaceutical Sciences
  • 2017/04 - 2018/03 Osaka University of Pharmaceutical Sciences
  • 2011/08 - 2017/03 Osaka University of Pharmaceutical Sciences
  • 2007/04 - 2011/07 Osaka City University University Hospital, Medical School
Show all
Committee career (1):
  • 2021/04 - 現在 日本薬学会 ファルマシアトピックス小委員
Awards (1):
  • 2020/01 - 日本薬学会関西支部 奨励賞 マクロファージにおける炎症誘導性細胞死の分子機構の解明
Association Membership(s) (4):
アメリカ細胞生物学会 ,  THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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