Rchr
J-GLOBAL ID:201901011735816354   Update date: Feb. 20, 2024

Iwasaki Takashi

イワサキ タカシ | Iwasaki Takashi
Affiliation and department:
Job title: Associate professor
Research field  (1): Bioorganic chemistry
Research keywords  (7): Genome editing ,  Protein engineering ,  Cell-penetrating peptide ,  細胞内輸送 ,  Drug delivery ,  Mammalian cell ,  Plant cell
Research theme for competitive and other funds  (10):
  • 2021 - 2025 Development of precise genome editing technology without genetic transformation or tissue culture in conifer species.
  • 2020 - 2023 ヒスチジン立体配置に基づいた細胞膜透過性タンパク質ファミリーの探索と機能解析
  • 2017 - 2020 Analysis for cell-penetrating mechanism of histidine-rich peptide/proteins
  • 2017 - 2020 Development of a gene recombination technique-free genome editing system in coniferous species
  • 2015 - 2018 Creation of micro-RNA-encapsulated artificial viral capsids bearing cell-penetrating ability
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Papers (33):
  • Masahiro Ono, Kenjiro Matsushita, Sho Maega, Naoto Asano, Yohei Matsunaga, Tomohiro Bito, Takashi Iwasaki, Tsuyoshi Kawano. The G protein-coupled receptor neuropeptide receptor-15 modulates larval development via the transforming growth factor-β DAF-7 protein in Caenorhabditis elegans. Biochemical and Biophysical Research Communications. 2023. 660. 28-34
  • Kentarou Sakamoto, Kohsuke Uchiyama, Takashi Iwasaki, Hiroshi Inaba, Kazunori Matsuura. An artificial viral capsid decorated with a DNA aptamer internalizing into lymphoma cells. Journal of Materials Chemistry B. 2023
  • Risako Une, Natsumi Kageyama, Masahiro Ono, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano. The FMRFamide-like peptide FLP-1 modulates larval development by regulating the production and secretion of the insulin-like peptide DAF-28 in Caenorhabditis elegans. Bioscience, Biotechnology, and Biochemistry. 2022. in press
  • Hiroshi Inaba, Yurina Sueki, Muneyoshi Ichikawa, Arif Md. Rashedul Kabir, Takashi Iwasaki, Hideki Shigematsu, Akira Kakugo, Kazuki Sada, Kazunori Matsuura. Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside. Science Advances. 2022. 8. eabq3817
  • Natsumi Kageyama, Masayo Nose, Masahiro Ono, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano. The FMRFamide-like peptide FLP-2 is involved in the modulation of larval development and adult lifespan by regulating the secretion of the insulin-like peptide INS-35 in Caenorhabditis elegans. Bioscience, Biotechnology, and Biochemistry. 2022. 86. 9. 1231-1239
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MISC (60):
  • 岩崎崇. 新規細胞膜透過ペプチドを利用したエクソソームノックダウン法の開発. 医科学応用研究財団研究報告(CD-ROM). 2022. 39
  • 末岐優里菜, 稲葉央, 岩崎崇, KABIR Arif Md. Rashedul, 角五彰, 佐田和己, 松浦和則. Stabilization of microtubules by encapsulation of tetrameric fluorescent proteins using Tau-derived peptides. 日本化学会春季年会講演予稿集(Web). 2021. 101st
  • 岩崎崇, 岩崎崇, 金山葉瑠, 下田麻由, 河野強, 河野強. Pathogenic mechanism of Histidine-rich protein 2 produced by Plasmodium falciparum. 日本農芸化学会大会講演要旨集(Web). 2021. 2021
  • 皆木友花, 粟津利邦, 松浦雅実, 松永洋平, 岩崎崇, 岩崎崇, 河野強, 河野強. Molecular mechanism of Rab-18, a small G-protein, in C. elegans larval development. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
  • 大村昂誠, 七里吉彦, 遠藤圭太, 河野強, 岩崎崇. Direct protein transport into model and non-model plant cells using Poly-His method. 日本農芸化学会大会講演要旨集(Web). 2020. 2020
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Patents (6):
  • 植物細胞に遺伝子を導入するための複合体
  • タンパク質を内包した人工微小管
  • 細胞膜透過ペプチドを利用した遺伝子組換えに頼らない植物ゲノム編集技術
  • 新規細胞膜透過ペプチド
  • 抗微生物ペプチドを固定化した素材
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Books (3):
  • 新しい細胞ペプチド『ポリヒスチジン』の発見と応用研究
    情報技術協会 2017
  • 抗菌ペプチドの機能解明と技術利用
    CMC出版 2017
  • 最新 昆虫病理学
    講談社 2014
Education (2):
  • 2005 - 2009 University of Tsukuba
  • 2001 - 2005 Hiroshima University Faculty of Science Department of Biological Science
Work history (4):
  • 2016/10 - 現在 Tottori University Faculty of Agriculture
  • 2010/04 - 2016/09 Tottori University Faculty of Agriculture
  • 2009/04 - 2010/03 日本学術振興会 特別研究員PD
  • 2007/04 - 2009/03 日本学術振興会 特別研究員DC1
Awards (10):
  • 2023/03 - 2022 B.B.B. paper award In vitro transcytosis of Helicobacter pylori histidine-rich protein through gastric epithelial-like cells and the blood-brain barrier
  • 2022/07 - Japanese Peptide Society Japanese Peptide Society Award for Young Investigator
  • 2022/03 - 2021 B.B.B. paper award Direct protein delivery into intact plant cells using polyhistidine peptides
  • 2014/09 - 日本農芸化学会 中四国支部 奨励賞
  • 2009/11 - 日本ペプチド学会 第46回ペプチド討論会 若手口頭発表優秀賞
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Association Membership(s) (4):
JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  Japanese Society for Plant Biotechnology ,  The Japanese Peptide Society ,  JAPAN SOCIETY FOR BIOSCIENCE
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