Chem
J-GLOBAL ID：201407052927720825   Nikkaji number：J3.320.942H

Capmatinib

カプマチニブ
Substance type：
Substance type
Substance type classified into 3 categories.
Decided structure: Substances with a clear structure
Undicided Structure: Substances with unknown or undetermined structure
Mixtures: Mixtures, racemic compounds, or compounds with relative structural arrangements
Decided structure
Molecular formula： C23H17FN6O
Molecular formula furigana： C23-H17-F-N6-O
Molecular weight： 412.428
InChI： InChI=1S/C23H17FN6O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20/h2-9,11-13H,10H2,1H3,(H,25,31)
InChI key： LIOLIMKSCNQPLV-UHFFFAOYSA-N
SMILES： CNC(=O)c1ccc(cc1F)c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1
Systematic name  (5)：
  • N-メチル-4-[7-(キノリン-6-イルメチル)-イミダゾ[1,2-b][1,2,4]トリアジン-2-イル]-2-フルオロベンズアミド
  • 2-フルオロ-N-メチル-4-[7-[(6-キノリニル)メチル]イミダゾ[1,2-b][1,2,4]トリアジン-2-イル]ベンズアミド
  • 2-フルオロ-N-メチル-4-{7-[(キノリン-6-イル)メチル]イミダゾ[1,2-b][1,2,4]トリアジン-2-イル}ベンズアミド
  • 2-fluoro-N-methyl-4-{7-[(quinolin-6-yl)methyl]imidazo[1,2-b][1,2,4]triazin-2-yl}benzamide
  • N-メチル-2-フルオロ-4-[7-(6-キノリルメチル)イミダゾ[1,2-b][1,2,4]トリアジン-2-イル]ベンズアミド
Other name (5)：
  • N-Methyl-4-[7-(quinoline-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazine-2-yl]-2-fluorobenzamide
  • INC-280
  • 2-Fluoro-N-methyl-4-[7-[(6-quinolinyl)methyl]imidazo[1,2-b][1,2,4]triazine-2-yl]benzamide
  • カプマチニブ
  • Capmatinib
Application (2)：
antitumor drug ,  non-smallcelllungcancer
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