大久保佳昭

オオクボヨシアキ | Okubo Yoshiaki

所属機関・部署：
職名：准教授

研究分野 (1件)：代謝、内分泌学

競争的資金等の研究課題 (2件)：

論文 (23件)：

Heather Torrey, Willem M Kühtreiber, Yoshiaki Okubo, Lisa Tran, Katherine Case, Hui Zheng, Eva Vanamee, Denise L Faustman. A novel TNFR2 agonist antibody expands highly potent regulatory T cells. Science signaling. 2020. 13. 661
Yuusuke Watanabe, Yoshifumi Saisho, Jun Inaishi, Kinsei Kou, Akira Yamauchi, Yasuhiko Kanazawa, Yoshiaki Okubo, Mikiya Tokui, Takatoshi Imai, Rie Murakami, et al. Efficacy and safety of once-weekly exenatide after switching from twice-daily exenatide in patients with type 2 diabetes. Journal of diabetes investigation. 2020. 11. 2. 382-388
Heather Torrey, John Butterworth, Toshiyuki Mera, Yoshiaki Okubo, Limei Wang, Danielle Baum, Audrey Defusco, Sara Plager, Sarah Warden, Daniel Huang, et al. Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs. Science signaling. 2017. 10. 462
Yoshiaki Okubo, Heather Torrey, John Butterworth, Hui Zheng, Denise L Faustman. Treg activation defect in type 1 diabetes: correction with TNFR2 agonism. Clinical & translational immunology. 2016. 5. 1. e56
Liqin Ban, Willem Kuhtreiber, John Butterworth, Yoshiaki Okubo, Éva S Vanamee, Denise L Faustman. Strategic internal covalent cross-linking of TNF produces a stable TNF trimer with improved TNFR2 signaling. Molecular and cellular therapies. 2015. 3. 7-7

MISC (5件)：

Yoshifumi Yamada, Kyoko Iwase, Akira Shimada, Yoshiaki Okubo, Yasuhiko Kanazawa, Junichiro Irie, Yoichi Oikawa, Toshihide Kawai, Hiroshi Hirose, Taro Maruyama, et al. FOXP3/Scurfin Gene Polymorphism Is Associated with Female Japanese Type 1 Diabetic Patients. DIABETES. 2009. 58. A590-A590
Yasohiko Kanazawa, Youichi Oikawa, Yoshiaki Okubo, Takatoshi Imai, Jyunichi Miyazaki, Akira Shimada, Hiroshi Itoh. Regulatory role of glutamic acid decarboxylase (GAD) reactive T cell in murine model of type 1 diabetes. DIABETES. 2008. 57. A354-A354
Kyoko Iwase, Toshihide Kawai, Yasuhiko Kanazawa, Yoshiaki Okubo, Yoichi Oikawa, Taro Maruyama, Akira Shimada, Hiroshi Ito. Foxp3/scurfin gene polymorphism in 'Adult' type 1 diabetes in Japanese. DIABETES. 2007. 56. A288-A288
Yoichi Oikawa, Toshikatsu Shigihara, Hiroyuki Yoneyama, Yasuhiko Kanazawa, Yoshiaki Okubo, Kouji Matsushima, Eiji Yamato, Jun-Ichi Miyazaki, Akira Kasuga, Takao Saruta, et al. The role of CXC chemokine ligand 10 in a spontaneous development of autoimmune diabetes in nonobese diabetic mice. DIABETES. 2006. 55. A280-A281
Yoshiaki Okubo, Yasuhiko Kanazawa, Yoichi Oikawa, Jun-Ichi Miyazaki, Akira Shimada. Islet hypertrophy observed in "reversed" diabetic NOD mouse after pancreatic beta cell line administration. DIABETES. 2006. 55. A281-A281

学歴 (1件)：

学位 (1件)：

経歴 (5件)：

2022/06 - 現在東京歯科大学市川総合病院内科准教授
2014/04 - 2022/05 東京歯科大学市川総合病院内科講師
2011/09 - 2014/03 東京歯科大学市川総合病院内科助教
2007/11 - 2011/08 Harvard Medical School, Massachusetts General Hospital Immunobiology Laboratory Research fellow
2003/06 - 2007/03 慶應義塾大学医学部内科学教室(腎臓内分泌代謝) 助手

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大久保 佳昭