東郷暁

トウゴウアキラ | Tohgo Akira

所属機関・部署：
職名：助手

研究分野 (1件)：病態医化学

競争的資金等の研究課題 (4件)：

cyclic ADP-ribose結合蛋白質の構造解析
ヒトFK506結合蛋白質の構造決定と転写調節の解明
Characterization of the gene encoding cyclic ADP-ribose binding protein
Structure and promoteranalysis of FK506 Binding protein 12.6

MISC (52件)：

F Ikehata, J Satoh, K Nata, A Tohgo, T Nakazawa, Kato, I, S Kobayashi, T Akiyama, S Takasawa, T Toyota, et al. Autoantibodies against CD38 (ADP ribosyl cyclase cyclic ADP ribose hydrolase) that impair glucose-induced insulin secretion in noninsulin-dependent diabetes patients. JOURNAL OF CLINICAL INVESTIGATION. 1998. 102. 2. 395-401
F Ikehata, J Satoh, K Nata, A Tohgo, T Nakazawa, Kato, I, S Kobayashi, T Akiyama, S Takasawa, T Toyota, et al. Autoantibodies against CD38 (ADP ribosyl cyclase cyclic ADP ribose hydrolase) that impair glucose-induced insulin secretion in noninsulin-dependent diabetes patients. JOURNAL OF CLINICAL INVESTIGATION. 1998. 102. 2. 395-401
K. Yagui, F. Shimada, M. Mimura, N. Hashimoto, Y. Suzuki, Y. Tokuyama, K. Nata, A. Tohgo, F. Ikehata, S. Takasawa, et al. A missense mutation in the CD38 gene, a novel factor for insulin secretion: Association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro. Diabetologia. 1998. 41. 9. 1024-1028
TAKASAWA S, NATA K, KUROKI M, TOHGO A, NOGUCHI N, KOBAYASHI S, KATO I, KATADA T, OKAMOTO H. Cyclic ADP-ribose and inositol 1,4,5-trisphosphate as alternate second messengers for intracellualr Ca²⁺ mobilization in normal and diabetic β-cells. The Journal of Biological Chemistry. 1998. 273. 5. 2497-2500
K. Yagui, F. Shimada, M. Mimura, N. Hashimoto, Y. Suzuki, Y. Tokuyama, K. Nata, A. Tohgo, F. Ikehata, S. Takasawa, et al. A missense mutation in the CD38 gene, a novel factor for insulin secretion: Association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro. Diabetologia. 1998. 41. 9. 1024-1028

書籍 (2件)：

A role of cyclic ADP-ribose, a NAD<SUP>+</SUP> metabolite, in stimulus-secretion coupling in pancreatic B-cell.
Frontiers of Insulin Secretion and Pancreatic B-Cell Research (Fratt, P. and Lenzen, S., eds.), Smith-Gordon 1995
A role of cyclic ADP-ribose, a NAD<SUP>+</SUP> metabolite, in stimulus-secretion coupling in pancreatic B-cell.
Frontiers of Insulin Secretion and Pancreatic B-Cell Research (Fratt, P. and Lenzen, S., eds.), Smith-Gordon 1995

学位 (1件)：

医学博士

受賞 (2件)：

1998 - 東北大学医学部奨励賞銀賞
1996 - 第33回ベルツ賞

所属学会 (2件)：

日本糖尿病学会 , 日本生化学会

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