研究者
J-GLOBAL ID:200901008593086894   更新日: 2024年01月30日

SHEIKH MOHAMMAD FAZLE AKBAR

Akbar Sheikh Mohammad | Sheikh Mohammad Fazle Akbar
所属機関・部署:
研究分野 (5件): 実験動物学 ,  応用微生物学 ,  免疫学 ,  実験病理学 ,  消化器内科学
研究キーワード (8件): Re-purposing immune modulators for pre-exposure and post-exposer prophylaxes and treatment of SARS-CoV-2 and COVID-19 ,  Accomplishment of phase/II/II clinical trials with immune therapeutic agent for chronic hepatitis B ,  Immune therapy for chronic hepatitis B and hepatocellular carcinoma ,  Preparation of antigen-presenting dendritic cells and use for treatment ,  Development of immune therapy for chronic hepatitis B virus infection in mouse model ,  Elucidation role of antigen-presenting cells in autoimmunity ,  Role of antigen-presenting dendritic cells in multiple pathologies ,  Mechanism of pathogenesis underlying chronic infection and cancer
競争的資金等の研究課題 (8件):
  • 2005 - 2006 原発性胆汁性肝硬変に対する免疫寛容誘導樹状細胞を用いた治療法の開発
  • 2002 - 2003 C型慢性肝炎に対する樹状細胞が産生する内因性インターフェロンを用いた治療法の開発
  • 持続感染における抗原提示樹状細胞
  • Antigen presenting Cells and neonatal tolerance
  • B型慢性肝疾患におけるワクチン治療
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論文 (197件):
  • Mamun Al Mahtab, Musarrat Mahtab, Md Abdur Rahim, Sheikh Mohammad Fazle Akbar, Sakirul Khan, Takaaki Yahiro, Shohael Mahmud Arafat, Mohammad Abdus Sattar Sarker, Provat Kumar Podder, Mohammad Shawkat Hossain, et al. Recent Dengue Infection in Bangladesh: A Seasonal Endemic Progressing to Year-long Serious Health Concern. Euroasian journal of hepato-gastroenterology. 2023. 13. 2. 145-151
  • Kana Shiraishi, Osamu Yoshida, Yusuke Imai, Sheikh Mohammad Fazle Akbar, Takahiro Sanada, Michinori Kohara, Takashi Miyazaki, Taizou Kamishita, Teruki Miyake, Masashi Hirooka, et al. Intranasal HBsAg/HBcAg-Containing Vaccine Induces Neutralizing Anti-HBs Production in Hepatitis B Vaccine Non-Responders. Vaccines. 2023. 11. 9
  • Sheikh Mohammad Fazle Akbar, Mamun Al Mahtab, Osamu Yoshida, Julio Aguilar, Guillen Nieto Gerardo, Yoichi Hiasa. Development of Therapy Based on the Exploration of Biological Events Underlying the Pathogenetic Mechanisms of Chronic Hepatitis B Infection. Biomedicines. 2023. 11. 7
  • Mamun Al-Mahtab, Sheikh Mohammad Fazle Akbar, Osamu Yoshida, Julio Cesar Aguilar, Gerardo Guillen, Yoichi Hiasa. Antiviral Response across Genotypes after Treatment of Chronic Hepatitis B Patients with the Therapeutic Vaccine NASVAC or Pegylated Interferon. Vaccines. 2023. 11. 5
  • Sheikh Mohammad Fazle Akbar, Mamun Al Mahtab, Sakirul Khan. Cellular and Molecular Mechanisms of Pathogenic and Protective Immune Responses to SARS-CoV-2 and Implications of COVID-19 Vaccines. Vaccines. 2023. 11. 3. 615-615
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MISC (43件):
  • S. M. F. Akbar, S. Chen, M. Al-Mahtab, T. Miyake, Y. Hiasa. MYELOID-DERIVED SUPPRESSOR CELLS AND DENDRITIC CELLS FOR IMPAIRED RESPONSE TO VACCINE IN MICE WITH NONALCOHOLIC FATTY LIVER DISEASE. JOURNAL OF HEPATOLOGY. 2014. 60. 1. S143-S144
  • Chen Shiyi, Sheikh Mohammad Fazle Akbar, 阿部 雅則, 日浅 陽一, 恩地 森一. B型肝炎 HBVキャリアマウスモデルにおける肝Myeloid-derived suppressor cell(MDSC)の機能. 肝臓. 2012. 53. Suppl.1. A329-A329
  • Shiyi Chen, Sheikh Mohammad Fazle Akbar, Masanori Abe, Yoichi Hiasa, Morikazu Onji. HEPATIC MYELOID-DERIVED SUPPRESSOR CELLS CONTROLLING INTRAHEPATIC IMMUNITY IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS. HEPATOLOGY. 2011. 54. 1110A-1110A
  • S. M. F. Akbar, S. Furukawa, N. Horiike, M. Abe, Y. Hiasa, M. Onji. Safety and immunogenicity of hepatitis B surface antigen-pulsed dendritic cells in patients with chronic hepatitis B. JOURNAL OF VIRAL HEPATITIS. 2011. 18. 6. 408-414
  • Chen Shiyi, Fazle Akbar, 阿部 雅則, 日浅 陽一, 恩地 森一. 肝臓におけるMyeloid-derived suppressor cell(MDSC)の機能解析. 肝臓. 2011. 52. Suppl.1. A280-A280
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特許 (3件):
  • B型肝炎ワクチン経鼻投与システム
  • 経鼻B型肝炎ワクチン組成物およびその製造方法,
  • 2006-512091
書籍 (8件):
  • Practical Hepato-Gastroenterology Prescriber
    Macmilan Medical Communications 2016
  • Companion to Hepatitis Management
    Macmilan Medical Communications 2016
  • Hepatitis Management Update
    Macmilan Medical Communications 2015
  • Textbook of Hepatogastroenterology
    Jaypee Brothers Medical Publishers, India 2015
  • Comprehensive Text Book of Hepatitis B
    Jaypee Brothers Medical Publishers, India 2010
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講演・口頭発表等 (91件):
  • Therapeutic vaccination and innovative strategies to treat CHB
    (30th Annual Meeting of INASL - 2022, Delhi, India 2022)
  • NASVAC - immune thrapy for chronic hepatitis B
    (18 th National Hepato Gastroenterology Congress on May 12-15,2022 Noah’s Ark Hotel and Congress Center, T.R.N.C. 2022)
  • AMED
    (研究課題:B型肝炎ウイルスの感染複製機構の解明に関する研究 2022)
  • Re-purposing HBV therapy for COVID-19
    (EGACON 2021, 18th Annual Conference of Euroasian Gastroenterological Association, Dhaka, Bangladesh 2021)
  • Immune Therapy: Can it be the Game Changer for Hepatitis B
    (SAASL 2021 8th Annual Conference of South Asian Association for the Study of the Liver 2021)
もっと見る
Works (2件):
  • Phase I/II/and III clinical trials in Patients with chronic hepatitis
    2009 - 現在
  • KIT development for Dendritic Cells
    2005 - 2006
学歴 (4件):
  • - 1993 愛媛大学
  • 1987 - 1988 Osaka University of Foreign Language
  • 1980 - 1981 Institute of Post Graduate Medicine and Research
  • 1980 - 1980 Rajshahi Medical College
学位 (1件):
  • Ph. D. in Medical Sciences
経歴 (13件):
  • 2020/04 - 現在 Ehime University Graduate School of Medicine Department of Gastroenterology and Metabology
  • 2018/06 - 2020/03 Ehime University Graduate School of Medicine Department of Analytical Pathology Proteo-Science Center
  • 2018/04 - 2018/05 Ehime University Graduate School of Medicine
  • 2008/04 - 2018/03 Toshiba General Hospital Department of Medical Sciences
  • 1996/11 - 2008/03 Ehime University Graduate School of medicine Department of Gastroenterology and Metabology
全件表示
委員歴 (1件):
  • 2018 - 現在 Miyakawa Memorial Research Foundation Councilor
受賞 (5件):
  • 2021/08 - Indian National Association for the Study of the Liver Dr. S R Naik Memorial Oration Dr. S R Naik Memorial Oration
  • 2019/04 - Cuban Academy of Science National Award, Cuban Academy of Science
  • 2017/07 - KALINGA GASTROENTEROLOGY FOUNDATION. Blumberg Oration
  • 2016/04 - Euroasian Gastroenterological Association Order of Merit
  • 2004 - Kyoto Liver Forum
所属学会 (9件):
Japan Dendritic Cell Society ,  The European Association for the Study of the Liver ,  The Americal Association for the Study of Liver Diseases ,  Japanese Society for Immunology ,  The Japanese Society of Gastroenterology ,  Japan Dendritic Cell Society ,  Japanese Society for Immunology ,  The Japanese Society of Gastroenterology ,  The Japan Society of Hepatology
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