橋口 美津子

• 2004 - 2010 アルツハイマー病の神経細胞死とタウリン酸化の制御機構および14-3-3たんぱく質による調節機構の研究
• 末梢神経変性疾患における神経線維のリン酸化調節機構
• Establishment of antibodies against modulation of tau phosphorylation.
• Mechanism of histamine-induced cell shape and microfilament in endothelial cells.
• Mechanisms of neurofilament phosphorylation of peripheral nerve degeneration.
Modulation of tau phosphorylation in Alzheimer's disease

• Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau. Journal of Biological Chemistry. 2003. 278(2): 1388
• M Hashiguchi, T Saito, S Hisanaga, T Hashiguchi. Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser(202)/Thr(205) of human tau. JOURNAL OF BIOLOGICAL CHEMISTRY. 2002. 277. 46. 44525-44530
• M Hashiguchi, T Saito, S Hisanaga, T Hashiguchi. Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser(202)/Thr(205) of human tau. JOURNAL OF BIOLOGICAL CHEMISTRY. 2002. 277. 46. 44525-44530
• 14-3-3z is an effector of tau protein phosphorylation. Journal of Biological Chemistry. 2000. 275: 25247-25254
• 14-3-3z Is an Effector of Tau Protein Phosphorylation. The Journal of Biological Chemistry. 2000. 275(33), 25247-25254

もっと見る

• 老化に伴うニューロフィラメント障害の発生機序と防御法の確立
  2000 -
• Prevention of aging-induced disruption of neurofilaments
  2000 -

• 医学博士 (東京医科大学)

• 2003 - 東京医科大学 佐々記念賞

Society for Neuroscience ,  The American Society for Cell Biology ,  日本神経化学会 ,  日本癌学会 ,  日本生化学会 ,  日本生理学会 ,  The Japanese Cancer Association ,  The Physiological Society of Japan ,  The Japanese Society for Neurochemistry ,  The Japanese Biochemical Society ,  Society for Neuroscience ,  The American Society for Cell Biology