西原 眞杉

• 2017 - 2020 新規リソソームタンパク質による神経筋組織の恒常性維持機構の解明
• 2011 - 2016 脳内成長因子の生理作用と病態に関する研究
• 2008 - 2011 ステロイド/成長因子システムの中枢作用機構に関する研究
• 2005 - 2008 ステロイドと成長因子の共役による脳機能の維持と再生
• 2001 - 2005 性ステロイド中枢作用の分子機構に関する研究
Sex steroid actions in the brain, Brain control of growth and metabolism

• Yanbo Ma, Takashi Matsuwaki, Keitaro Yamanouchi, Masugi Nishihara. Involvement of progranulin in modulating neuroinflammatory responses but not neurogenesis in the hippocampus of aged mice. EXPERIMENTAL GERONTOLOGY. 2017. 95. 1-8
• T. Matsuwaki, M. Komatsuda, A. Fujisawa, M. Doke, K. Yamanouchi, M. Nishihara. Molecular species of prostaglandins involved in modulating luteinising hormone pulses of female rats under infectious stress conditions. JOURNAL OF NEUROENDOCRINOLOGY. 2017. 29. 7. 7
• Yanbo Ma, Takashi Matsuwaki, Keitaro Yamanouchi, Masugi Nishihara. Progranulin Protects Hippocampal Neurogenesis via Suppression of Neuroinflammatory Responses Under Acute Immune Stress. MOLECULAR NEUROBIOLOGY. 2017. 54. 5. 3717-3728
• Ken-ichi Kawashima, Yuri Ishiuchi, Miki Konnai, Saori Komatsu, Hitoshi Sato, Hideo Kawaguchi, Nobumitsu Miyanishi, Jerome Lamartine, Masugi Nishihara, Taku Nedachi. Glucose deprivation regulates the progranulin-sortilin axis in PC12 cells. FEBS OPEN BIO. 2017. 7. 2. 149-159
• Tsutiya A, Nakano Y, Hansen-Kiss E, Kelly BJ, Nishihara M, Goshima Y, Corsmeier D, White P, Herman GE, Ohtani-Kaneko R. Human Crmp4 mutation and disrupted Crmp4 expression in mice associated with ASD characteristics and sexual dimorphism. Sci Rep. 2017. 7. 16812

もっと見る

• Takashi Matsuwaki, Keitaro Yamanouchi, Masugi Nishihara. The effect of glucocorticoids on bradykinesia induced by immobilization stress. HORMONES AND BEHAVIOR. 2008. 54. 1. 41-46
• Ayako BAN, Keitaro YAMANOUCHI, Takashi MATSUWAKI, Masugi NISHIHARA. In vivo gene transfer of PPARg is insufficient to induce adipogenesis in skeletal muscle. J Vet Med Sci. 2008. 70. 8. 761-767
• Jae-hyek CHOI, Maho ISHIDA, Takashi MATSUWAKI, Keitaro YAMANOUCHI, Masugi NISHIHARA. Involvement of 20a-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice. J Reprod Dev. 2008. 54. 6. 408-412
• Yuko Kayasuga, Shuichi Chiba, Masatoshi Suzuki, Takefumi Kikusui, Takashi Matsuwaki, Keitaro Yamanouchi, Hayato Kotaki, Reiko Horai, Yoichiro Iwakura, Masugi Nishihara. Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene. BEHAVIOURAL BRAIN RESEARCH. 2007. 185. 2. 110-118
• Hitomi FUJIOKA, Keitaro YAMANOUCHI, Tatsuo AKEMA, Masugi NISHIHARA. The effects of GABA on embryonic gonadotropin-releasing hormone neurons in rat hypothalamic primary culture. J Reprod Dev. 2007. 53. 2. 323-331

もっと見る

• Controlling mechanism of GnRH pulse generator activity in the rat. In : Neural Control of the Reproduction : Physiology and Behavior.
  Japan Scientific Societies Press/Karger 1997
• In vivo electrophysiological monitoring of the GnRH pulse generator in rats and goats
  Pulsatility in Neuroendocrine Systems, Academic Press 1994

• 1977 - 1981 東京大学 大学院農学系研究科 畜産学専攻
• - 1979 東京大学
• 1973 - 1977 東京大学 農学部 畜産獣医学科
• - 1977 東京大学

• 農学博士

• 2000/04 - 現在 東京大学大学院農学生命科学研究科 教授
• 1991/01 - 2000/03 東京大学農学部 助教授
• 1981/04 - 1990/12 横浜市立大学医学部 助手

日本繁殖生物学会 ,  日本生殖内分泌学会 ,  日本神経内分泌学会 ,  米国神経科学会(Society for Neuroscience) ,  米国内分泌学会(The Endocrine Society) ,  日本畜産学会 ,  日本獣医学会 ,  International Society of Neuroendocrinology ,  Endocrine Society ,  Society for the Study of Reproduction ,  Society for Neuroscience ,  Japan Endocrine Society ,  Japanese Society of Animal Scienceı ,  Japanese Society of Veterinary Science ,  Society for Reproduction and Development