2003 - 2007 Analysis of drug transporters in rats with acute renal failure.
論文 (21件)：
Yasuto Kido, Isamu Nanchi, Takanobu Matsuzaki, Ryosuke Watari, Hayato Kiyohara, Naomi Seki, Tomohiko Okuda. Prediction of drug-drug interaction risk of P-glycoprotein substrate in drug discovery. Drug Metabolism and Pharmacokinetics. 2024
Ryosuke Watari, Hiromi Sawada, Hiroshi Hashimoto, Yasuyuki Kasai, Ryoko Oka, Ryosuke Shimizu, Takanobu Matsuzaki. Utility of Coproporphyrin-I Determination in First-in-Human Study for Early Evaluation of OATP1B Inhibitory Potential Based on Investigation of Ensitrelvir, an Oral SARS-CoV-2 3C-Like Protease Inhibitor. Journal of Pharmaceutical Sciences. 2024
Shimizu R, Sonoyama T, Fukuhara T, Kuwata A, Matsuzaki T, Matsuo Y, Kubota R. Evaluation of the Drug-Drug Interaction Potential of Ensitrelvir Fumaric Acid with Cytochrome P450 3A Substrates in Healthy Japanese Adults. Clinical drug investigation. 2023
Shimizu R, Matsuzaki T, Oka R, Sonoyama T, Fukuhara T, Kuwata A, Matsuo Y, Kubota R. Evaluation of drug-drug interactions of ensitrelvir, a SARS-CoV-2 3CL protease inhibitor, with transporter substrates based on in vitro and a clinical study. Journal of clinical pharmacology. 2023
Yasuto Kido, Isamu Nanchi, Yasuyuki Fusamae, Takanobu Matsuzaki, Takanori Akazawa, Hiromi Sawada, Makoto Iwasaki, Kimiko Nishida, Eiichi Tsuchiya, Tomohiko Okuda. Species difference in brain penetration of P-gp and BCRP substrates among monkey, dog and mouse. Drug metabolism and pharmacokinetics. 2022. 42. 100426-100426
