新宮多加志

シングウタカシ | Shingu Takashi

所属機関・部署：

研究分野 (2件)：脳神経外科学 , 腫瘍生物学

研究キーワード (8件)：タンパク質クエイキング , 3-D 細胞培養 , グリオーマ幹細胞 , 多核白金製剤 , 分子標的療法 , 膠芽腫 , グリオーマ , オートファジー

競争的資金等の研究課題 (1件)：

論文 (25件)：

Chao-Hsien Chen, Renee L Chin, Genevieve P Hartley, Spencer T Lea, Brian J Engel, Cheng-En Hsieh, Rishika Prasad, Jason Roszik, Takashi Shingu, Gregory A Lizee, et al. Novel murine glioblastoma models that reflect the immunotherapy resistance profile of a human disease. Neuro-Oncology. 2023. 25. 8. 1415-1427
Fatma Betul Aksoy Yasar, Takashi Shingu, Daniel B. Zamler, Mohammad Fayyad Zaman, Derek Lin Chien, Qiang Zhang, Jiangong Ren, Jian Hu. Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma. Frontiers in Cell and Developmental Biology. 2022. 10
Daniel B. Zamler, Takashi Shingu, Laura M. Kahn, Kristin Huntoon, Cynthia Kassab, Martina Ott, Katarzyna Tomczak, Jintan Liu, Yating Li, Ivy Lai, et al. Immune landscape of a genetically engineered murine model of glioma compared with human glioma. JCI Insight. 2022. 7. 12
Akira Inoue, Frederick S. Robinson, Rosalba Minelli, Hideo Tomihara, Bahar Salimian Rizi, Johnathon L. Rose, Takahiro Kodama, Sanjana Srinivasan, Angela L. Harris, Andy M. Zuniga, et al. Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer. Gastroenterology. 2021. 161. 1. 196-210
Seula Shin, Hao Zhou, Chenxi He, Yanjun Wei, Yunfei Wang, Takashi Shingu, Ailiang Zeng, Shaobo Wang, Xin Zhou, Hongtao Li, et al. Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency. Nature Communications. 2021. 12. 1

MISC (8件)：

Takashi Shingu, Jian Hu. QUAKING (QKI) LOSS ENHANCES GSC STEMNESS AND PROMOTES GLIOMAGENESIS THROUGH REGULATING INTRACELLULAR VESICLE TRAFFICKING. NEURO-ONCOLOGY. 2017. 19. 231-231
Jian Hu, Takashi Shingu. QKI DELETION ENHANCES SELF-RENEWAL OF GLIOMA STEM CELLS AND PROMOTES GLIOMAGENESIS. NEURO-ONCOLOGY. 2016. 18. 183-184
Jian Hu, Takashi Shingu, Liang Yuan. How glioma stem cells maintain sternness outside their niche. CANCER RESEARCH. 2016. 76
Takashi Shingu, Lindsay Holmes, Verlene Henry, Khatri Letha, Anupama E. Gururaj, Laura A. Gibson, Tiffany Doucette, Frederick F. Lang, Ganesh Rao, Liang Yuan, et al. Synergistic combination therapy with molecular targeted drugs in glioma stem-like cells. CANCER RESEARCH. 2015. 75
Takashi Shingu, Allen Ho, Liang Yuan, Jian Hu. QKI deletion enhances self-renewal of glioma stem cells and promotes gliomagenesis. CANCER RESEARCH. 2015. 75

学歴 (2件)：

学位 (1件)：

経歴 (5件)：

所属学会 (5件)：

米国がん学会 , 日本分子脳神経外科学会 , 日本脳神経外科学会 , 日本薬理学会 , 日本生化学会

※　J-GLOBALの研究者情報は、researchmapの登録情報に基づき表示しています。登録・更新については、こちらをご覧ください。

新宮 多加志