Mechanism of intracellular protein degradation mediated by ubiquitin and proteasomes
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論文 (596件):
Nodoka Nago, Shigeo Murata, Keiji Tanaka, Nobuyuki Tanahashi. Changes in brain proteasome dynamics associated with aging. Genes to Cells. 2024
Yoshino Akizuki, Mai Morita, Yuki Mori, Ai Kaiho-Soma, Shivani Dixit, Akinori Endo, Marie Shimogawa, Gosuke Hayashi, Mikihiko Naito, Akimitsu Okamoto, et al. cIAP1-based degraders induce degradation via branched ubiquitin architectures. Nature chemical biology. 2022. 19. 3. 311-322
Yoko Hasegawa, Thais Huarancca Reyes, Tomohiro Uemura, Anirban Baral, Akari Fujimaki, Yongming Luo, Yoshie Morita, Yasushi Saeki, Shugo Maekawa, Shigetaka Yasuda, et al. The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis. The Plant cell. 2022. 34. 4. 1354-1374
Bruno Barros Queliconi, Waka Kojima, Mayumi Kimura, Kenichiro Imai, Chisato Udagawa, Chie Motono, Takatsugu Hirokawa, Shinya Tashiro, Jose M. M. Caaveiro, Kouhei Tsumoto, et al. Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1. Journal of Cell Science. 2021. 134. 22
Yukiko Yoshida, Makoto Asahina, Arisa Murakami, Junko Kawawaki, Meari Yoshida, Reiko Fujinawa, Kazuhiro Iwai, Ryuichi Tozawa, Noriyuki Matsuda, Keiji Tanaka, et al. Loss of peptide:N-glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 27
2014 - Nobel Forum Lecture at Karolinska Institute
2014 - 「文化功労者」顕彰
2010 - 日本内分泌学会マイスター賞
2010 - 慶應医学賞
2010 - 徳島大学栄誉賞
2010 - 徳島新聞賞科学賞
2010 - 日本学士院賞
2009 - ナイスステップ研究者2009
2009 - 武田医学賞
2007 - 東レ科学技術賞
2005 - 東京スピリット賞
2004 - 上原賞
2004 - 朝日賞
2003 - 内藤記念科学振興賞
1998 - 日本生化学会奨励賞受賞:プロテアソーム
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所属学会 (9件):
日本蛋白質科学会
, 日本免疫学会
, 日本分子生物学会
, 日本生化学会
, 日本癌学会
, The Japanese Society of Immunology
, Japanese Molecular Biology Association
, Japanese Cancer Association
, Japanese Biochemical Society