小口健史

Takeshi Oguchi

研究分野 (1件)：麻酔科学

研究キーワード (3件)：プロタミン , インスリン , 心筋虚血

競争的資金等の研究課題 (9件)：

2024 - 2027 GLP-1受容体からみたイリドイド配糖体の心筋虚血再灌流障害に対する心保護作用の解明
2023 - 2026 心筋虚血再灌流障害に対するGLP-1の濃度依存性の心保護作用の解明
2022 - 2025 人工心肺が惹起する急性炎症と認知機能障害に対する経鼻インスリンの効果と機序の解明
2021 - 2024 PI3K/Akt経路からみたラクトフェリンの気絶心筋に対する保護効果の検討
2020 - 2023 PI3K/Akt経路からみた虚血再灌流障害に対するフラボノイドの心筋保護効果

全件表示

論文 (91件)：

Yosuke Nakadate, Akiko Kawakami, Takeshi Oguchi, Keisuke Omiya, Hiroyuki Nakajima, Hiroshi Yokomichi, Hiroaki Sato, Thomas Schricker, Takashi Matsukawa. Safety of intranasal insulin administration in patients undergoing cardiovascular surgery: An open-label, nonrandomized, dose-escalation study. JTCVS Open. 2024. 17. 172-182
Keisuke Omiya, Yosuke Nakadate, Hiroaki Sato, Takeshi Oguchi, Toru Matsuoka, Akiko Kawakami, Thomas Schricker, Takashi Matsukawa. Role of the protein kinase A signaling pathway and identification of mediators in the cardioprotective effects of enteral lactoferrin for ischemia-reperfusion injury in an isolated rat heart model. Nutrition. 2023. 113. 112088-112088
Yosuke Nakadate, Akiko Kawakami, Hiroaki Sato, Tamaki Sato, Takeshi Oguchi, Keisuke Omiya, Toru Matsuoka, Thomas Schricker, Takashi Matsukawa. PI3K/Akt pathway mediates the positive inotropic effects of insulin in Langendorff-perfused rat hearts. Scientific Reports. 2022. 12. 1
Keisuke Omiya, Yosuke Nakadate, Takeshi Oguchi, Tamaki Sato, Toru Matsuoka, Masako Abe, Akiko Kawakami, Takashi Matsukawa, Hiroaki Sato. Cardioprotective effects of enteral vs. parenteral lactoferrin administration on myocardial ischemia-reperfusion injury in a rat model of stunned myocardium. BMC Pharmacology and Toxicology. 2022. 23. 1
Yosuke Nakadate, Emi Nakajima, Kodai Ikemoto, Takeshi Oguchi, Takashi Matsukawa. Anesthetic experience does not reduce accidental dural puncture in surgical patients: a retrospective case-controlled study. BMC anesthesiology. 2022. 22. 1. 139-139

MISC (24件)：

ISHIYAMA Tadahiko, IIJIMA Tetsuya, SUGAWARA Takeshi, OGUCHI Takeshi, KASHIMOTO Satoshi. Effects of 1% Glucose-Containing Ringer's Solution on Intraoperative Plasma Glucose Concentration in Elderly and Young Patients. 循環制御 = CIRCULATION CONTROL. 2006. 27. 3. 232-235
石山忠彦, 飯嶋哲也, 市川学, 古屋敦司, 吉良聡, 三塚健太郎, 長嶺教光, 福島久史, 三谷茂樹, 菅原健, et al. 術後急性痛の治療. 臨床麻酔. 2005. 29. 1. 75-80
K Masui, S Kashimoto, A Furuya, T Oguchi, T Kumazawa. Free radical scavenger with inhalation anesthetic prevents recovery from ischemia in rat hearts. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2003. 35. 11. A34-A34
福島久史, 石山忠彦, 小口健史, 増井健一, 樫本温, 熊澤光生, 杉田正夫. プロポフォール麻酔下での脳腫瘍摘出術中に頻繁に痙攣発作をきたした1症例. 麻酔. 2003. 52. 7. 804-804
A Furuya, S Kashimoto, T Oguchi, K Masui, T Kumazawa. Effects of nicorandil on myocardial function and metabolism in the ischemic heart with or without inhalation anesthetics. ANESTHESIOLOGY. 2000. 93. 3A. U170-U170

講演・口頭発表等 (40件)：

Safety Trial of Intranasal Insulin Administration for Cardiac Surgery Patients: Dose Escalation Study
(American Society of Anesthesiologists Annual Meeting 2022 2022)
人工心肺を用いる開心術におけるレミフェンタニル使用量と術後IL-6の関係
(日本麻酔科学会第69回学術集会 2022)
Can Experience Reduce Accidental Dural Puncture?
(American Society of Anesthesiologists Annual Meeting 2021 2021)
Lactoferrin Attenuates Myocardial Ischemia-reperfusion Injury Via Protein Kinase A Pathway
(American Society of Anesthesiologists Annual Meeting 2021 2021)
Airway management of differential lung ventilation for a tracheal stenosis patient caused by large thoracic anterior osteophytes
(The 68th Annual Meeting of the Japanese Society of Anesthesiologists 2021)

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