小林浩

コバヤシヒロシ | Kobayashi Hiroshi

所属機関・部署：
ホームページURL (1件)： http://www.naramed-u.ac.jp/~gyne

研究分野 (1件)：産婦人科学

研究キーワード (6件)：羊水塞栓症 , 腫瘍マーカー , 癌転移抑制 , Amniotic fluid embolism , Tumor markers , Cancer invasion and metastasis

競争的資金等の研究課題 (71件)：

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論文 (33件)：

M Suzuki, H Kobayashi, Y Tanaka, N Kanayama, T Terao. Reproductive failure in mice lacking inter-alpha-trypsin inhibitor (ITI) - ITI target genes in mouse ovary identified by microarray analysis. JOURNAL OF ENDOCRINOLOGY. 2004. 183. 1. 29-38
Y Tanaka, H Kobayashi, M Suzuki, N Kanayama, M Suzuki, T Terao. Upregulation of bikunin in tumor-infiltrating macrophages as a factor of favorable prognosis in ovarian cancer. GYNECOLOGIC ONCOLOGY. 2004. 94. 3. 725-734
M Suzuki, H Kobayashi, N Kanayama, Y Saga, M Suzuki, CY Lin, RB Dickson, T Terao. Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase. JOURNAL OF BIOLOGICAL CHEMISTRY. 2004. 279. 15. 14899-14908
Y Tanaka, H Kobayashi, M Suzuki, Y Hirashima, N Kanayama, T Terao. Genetic downregulation of pregnancy-associated plasma protein-A (PAPP-A) by bikunin reduces IGF-I-dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis. INTERNATIONAL JOURNAL OF CANCER. 2004. 109. 3. 336-347
Y Tanaka, H Kobayashi, M Suzuki, N Kanayama, T Terao. Transforming growth factor-beta 1-dependent urokinase up-regulation and promotion of invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer cells. JOURNAL OF BIOLOGICAL CHEMISTRY. 2004. 279. 10. 8567-8576

MISC (80件)：

特許 (1件)：

書籍 (5件)：

Clear cell carcinoma of the ovary: potential pathogenic mechanisms
Oncol Rep. 2010
Fatal Factors of Clinical Manifestations and Laboratory Testing in Patients with Amniotic Fluid Embolism.
Gynecol Obstet Invest. 2010
Anti-inflammatory actions of serine protease inhibitors containing the Kunitz domain.
Inflamm Res. 2010
Screening, epidemiology, molecular biology, and treatment strategies for endometriosis-associated ovarian cancer.
Reprod. Med. Biol. 2010
Nidogen-2: A new serum biomarker for ovarian cancer.
Clin Biochem. 2010

Works (2件)：

Increased cell-surface urokinase in advanced ovarian cancer
1993 -
Saturation of tumor cell surface receptors for uPA by ATF and subsequent effect on reconstitutied BM invasion
1993 -

学歴 (2件)：

学位 (1件)：

経歴 (10件)：

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委員歴 (3件)：

受賞 (2件)：

所属学会 (9件)：

がん転移学会 , 日本血栓止血学会 , 日本血液学会 , 日本新生児学会 , 日本不妊学会 , American Association for Cancer Research , 日本癌学会 , 日本癌治療学会 , 日本産科婦人科学会

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小林 浩