舟本聡

フナモトサトル | Funamoto Satoru

所属機関・部署：
職名：准教授

研究分野 (1件)：神経形態学

研究キーワード (8件)：ホスフォイノシチド , ガンマセクレターゼ , アルツハイマー病 , アミロイドβ , phosphoinositides , gamma-secretase , Alzheimer Disease , Amyloid beta protein

競争的資金等の研究課題 (12件)：

全件表示

論文 (37件)：

Sato W, Watanabe-Takahashi M, Murata T, Utsunomiya-Tate N, Motoyama J, Anzai M, Ishihara S, Nishioka N, Uchiyama H, Togashi J, et al. A tailored tetravalent peptide displays dual functions to inhibit amyloid β production and aggregation. Commun. Biol. 2023. 6(1)383. 1. 383-383
Rikuya Yoshimura, Tomohiro Miyasaka, Satoru Funamoto, Takashi Saito, Takaomi C Saido, Masaya Ikegawa, Nobuto Kakuda. The senile plaque: Morphological differences in APP knock-in mice brains by fixatives. Brain and behavior. 2023. e2953
Waka Sato, Miho Watanabe-Takahashi, Takashi Hamabata, Koichi Furukawa, Satoru Funamoto, Kiyotaka Nishikawa. A nontoxigenic form of Shiga toxin 2 suppresses the production of amyloid β by altering the intracellular transport of amyloid precursor protein through its receptor-binding B-subunit. Biochemical and Biophysical Research Communications. 2021. 557. 247-253
Shahnur Alam, Masaki Nakano, Seiko Ishihara, Nobuto Kakuda, Tomohiro Miyasaka, Hina Uchiyama, Yuuna Shirai, Mohammad Moniruzzaman, Takashi Saito, Takaomi C. Saido, et al. A Potential Defense Mechanism Against Amyloid Deposition in Cerebellum. Biochemical and Biophysical Research Communications. 2021. 535. 25-32
Satoru Funamoto, Shinji Tagami, Masayasu Okochi, Maho Morishima-Kawashima. Successive cleavage of β-amyloid precursor protein by γ-secretase. Seminars in Cell & Developmental Biology. 2020. 105. 64-74

MISC (37件)：

特許 (5件)：

書籍 (8件)：

デブリン生化学
丸善出版 2013
Equimolar production of Aβ and AICD from C99 by γ-secretase
2006
Equimolar production of Aβ and AICD from C99 by γ-secretase
10th International Conference on Alzheimer's Disease and Related Disorders Alzheimer's Disease : New Advances 2006
Directional sensing : Subcellular targeting of GPCR downstream effectors during chemotaxis In : Cell Motility : From Molecules to Organisms
2004
Directional sensing : Subcellular targeting of GPCR downstream effectors during chemotaxis In : Cell Motility : From Molecules to Organisms
John Wiley & Sons, Ltd 2004

講演・口頭発表等 (25件)：

抗アミロイド療法としてのAPP特異的切断抑制
(第42回日本認知症学会学術集会 2023)
副作用のない抗アミロイド療法の開発
(第96回日本生化学会大会シンポジウム 2S03e 2023)
Potential determination mechanism of epsilon-cleavage sites: Implication for determinants of Abeta40 and Abeta42 product lines
(ADPD2017 2017)
APP A673T mutation reduces not only b-cleavage but also g-cleavage of APP in cells
(ADPD2015 2015)
アミロイドβの産生機序と産生抑制
(認知症の最新発症メカニズムと治療薬開発 2015)

学位 (2件)：

経歴 (4件)：

委員歴 (1件)：

受賞 (2件)：

所属学会 (4件)：

米国神経科学会 , 日本分子生物学会 , SFN , Molecular Biology Society of Japan

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舟本 聡