研究者
J-GLOBAL ID:200901051946750885
更新日: 2022年10月01日
山口 陽子
ヤマグチ ヨウコ | Yamaguchi Yoko
所属機関・部署:
職名:
客員教授
ホームページURL (1件):
http://www.cityofhope.org/people/fujita-yamaguchi-yoko
研究分野 (2件):
機能生物化学
, 構造生物化学
研究キーワード (5件):
放線菌由来のレクチンSHAの復活研究
, 糖鎖特異的単鎖抗体の発現・解析
, IGF-I recptor signaling
, がん分子標的治療法
, Molecular targeted-strategy utilizing antibodies against carbohydrates and IGF-I receptor
競争的資金等の研究課題 (6件):
論文 (24件):
-
Yoko Fujita-Yamaguchi, Hideyuki Muramatsu, Alonso Tapia, Karine Bagramyan, Moksha Desai, Yasuhiro Takehana, Masayuki Igarashi, Yoshiki Yamaguchi, Markus Kalkum. Proteolytic Processing, Maturation, and Unique Synteny of the Streptomyces Hemagglutinin SHA. Microbiology spectrum. 2021. 9. 2. e0076621
-
Naoki Takizawa, Yoshitoshi Ogura, Yoko Fujita, Takeshi Noda, Hideki Shigematsu, Tetsuya Hayashi, Ken Kurokawa. Local structural changes of the influenza A virus ribonucleoprotein complex by single mutations in the specific residues involved in efficient genome packaging. Virology. 2019. 531. 126-140
-
Fujita-Yamaguchi Y, Bagramyan K, Yamaguchi Y, Ikeda A, Dohmae N, Hong TB, Kalkum M. Mass spectrometric revival of an l-rhamnose- and d-galactose-specific lectin from a lost strain of Streptomyces. The Journal of biological chemistry. 2018. 293. 1. 368-378
-
Nakata M, Kawaguchi S, Oikawa A, Inamura A, Nomoto S, Miyai H, Nonaka T, Ichimi S, Fujita-Yamaguchi Y, Luo C, et al. An aqueous extract from toad skin prevents gelatinase activities derived from fetal serum albumin and serum-free culture medium of human breast carcinoma MDA-MB-231 cells. Drug discoveries & therapeutics. 2016. 9. 6. 417-421
-
Hirose-Yotsuya L, Okamoto F, Yamakawa T, Whitson RH, Fujita-Yamaguchi Y, Itakura K. Knockdown of AT-rich interaction domain (ARID) 5B gene expression induced AMPKα2 activation in cardiac myocytes. Bioscience trends. 2015. 9. 6. 377-385
もっと見る
MISC (166件):
-
Yoko Fujita-Yamaguchi, Yoshiki Yamaguchi, Akemi Ikeda, Naoshi Domae, Karine Bagramyan, Teresa B. Hong, John P. Murad, Markus Kalkum. Primary structure determination of a blood group B-specific lectin purified from Streptomyces sp 27S5 reveals insight into its mechanism of expression and unique structural features. GLYCOBIOLOGY. 2016. 26. 12. 1415-1415
-
Markus Kalkum, Teresa Hong, Karine Bagramyan, Yoko Fujita-Yamaguchi. Proteomics and Genomics Provide Novel Insights Into Streptomyces Lectin Biochemistry. GLYCOBIOLOGY. 2014. 24. 11. 1115-1116
-
Yoko Fujita-Yamaguchi, Astufumi Nakazawa, Noriyuki Yuasa. Expression and Purification of Anti-IGF-I Receptor 1H7 Constructs in Drosophila S2 Cells. ENDOCRINE REVIEWS. 2014. 35. 3
-
Hiroyuki Kato, Takahito Fukuda, Noriyuki Yuasa, Yoko Fujita-Yamaguchi. Expression, purification, and refolding of single chain antibodies (scFvs) from inclusion bodies. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012. 244
-
Tsubasa Koyama, Daisuke Takada, Yoshiki Yamaguchi, Noriyuki Yuasa, Ayano Matsumoto-Takasaki, Yoko Fujita-Yamaguchi. In vitro production of anticarbohydrate antibodies: Purification of anti-T antigen antibodies (scFvs) from E. coli inclusion bodies and Drosophila S2 cell culture media. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012. 244
もっと見る
書籍 (6件):
-
Isolation and characterization of antibodies against three consecutive Tn-antigen clusters from a phage library displaying human single-chain variable fragments.
J. Biochem. (Sakai, K., Yuasa, N., Tsukamoto, K., Takasaki-Matsumoto, A., Yajima, Y., Sato, R., Kawakami, H., Mizuno, M., Takayanagi, A., Shimizu, N., Nakata, M., and Fujita-Yamaguchi, Y. ) 2010
-
Preparation of asialo-agalacto-glycophorin A for screening of anti-Tn antibodies.
Biosci. Trends. Koizumi, T., Matsumoto-Takasaki, A., Nakada, H., Nakata, M., Fujita-Yamaguchi, Y. 2010
-
Production of anti-carbohydrate antibodies by phage-display technologies: Potential impairment of cell growth as a result of endogenous expression.
J. Biol. Chem. (Yuasa, N., Zhang, W., Goto, T., Sakaue, H., Matsumoto- Takasaki, A., Kimura, M., Ohshima, H., Tsuchida, Y., Koizumi, T., Sakai, K., Kojima, T., Yamamoto, K., Nakata, M., and Fujita-Yamaguchi, Y.) 2010
-
Preparation of asialo-agalacto-glycophorin A for screening of anti-Tn antibodies.
Biosci. Trends. (Koizumi, T., Matsumoto-Takasaki, A., Nakada, H., Nakata, M., Fujita-Yamaguchi, Y.) 2010
-
Production of anti-carbohydrate antibodies by phage-display technologies: Potential impairment of cell growth as a result of endogenous expression.
J. Biol. Chem. (110) Yuasa, N., Zhang, W., Goto, T., Sakaue, H., Matsumoto- Takasaki, A., Kimura, M., Ohshima, H., Tsuchida, Y., Koizumi, T., Sakai, K., Kojima, T., Yamamoto, K., Nakata, M., and Fujita-Yamaguchi, Y.) 2010
もっと見る
学歴 (6件):
- - 1977 東京大学 農学系研究科 農芸化学
- - 1977 東京大学
- - 1973 東京大学 農学系研究科 農芸化学
- - 1973 東京大学
- - 1971 埼玉大学 理工学部 生化学
- - 1971 埼玉大学
全件表示
学位 (1件):
経歴 (8件):
- 2022/05 - 現在 順天堂大学 大学院医学研究科 客員教授
- 2014/04 - 現在 City of Hope ベックマン研究所 Diabetes & Metabolism Res. Inst. Professor Emeritus
- 2000 - 2014/03 東海大学工学部生命化学科教授 & 米国City of Hopeベックマン研究所Adjunct Professor of Molecular Biology
- 1981 - 2000 米国City of Hopeベックマン研究所Assistant ProfessorからProfessor of Molecular Biology
- 1981 - 2000 Assistant Professor to Professor of Molecular Biology at Beckman Research Institute of the City of Hope
- 2000 - - Professor of Applied Biochemistry, School of Engineering, Tokai University & Adjunct Professor of Molecular Biology at Beckman Research Institute of the City of Hope
- 1977 - 1981 米国City of Hope研究所 博士研究員
- 1977 - 1981 Research Fellow at City of Hope Medical Center
全件表示
所属学会 (3件):
アメリカ内分泌学会(The Endocrine Society)
, 日本生化学学会
, アメリカ生化学・分子生物学会(American Society for Biochemistry and Molecular Biology)
前のページに戻る