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J-GLOBAL ID：201202262527956252   整理番号：12A1616492

アペリン(APJ)受容体の機能的な拮抗薬としての4-オキソ-6-((ピリミジン-2-イルチオ)メチル)-4H-ピラン-3-イル4-ニトロベンゾアート(ML221)の発見

Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor

著者 (24件)： MALONEY Patrick R. (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  KHAN Pasha (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  HEDRICK Michael (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  GOSALIA Palak (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  MILEWSKI Monika (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  LI Linda (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  ROTH Gregory P. (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  SERGIENKO Eduard (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  SUYAMA Eigo (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  SUGARMAN Eliot (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  NGUYEN Kevin (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  MEHTA Alka (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  VASILE Stefan (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  SU Ying (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  STONICH Derek (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  NGUYEN Hung (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  ZENG Fu-yue (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  NOVO Arianna Mangravita (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  VICCHIARELLI Michael (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  DIWAN Jena (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  CHUNG Thomas D.Y. (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...) ,  SMITH Layton H. (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 6400 Sanger Road, Orlando, FL 32827, USA) ,  SMITH Layton H. (Cardiopathobiology Program, Diabetes and Obesity Res. Center, Sanford Burnham Medical Res. Inst. at Lake Nona, 6400 ...) ,  PINKERTON Anthony B. (Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Res. Inst., 10901 North Torrey Pines Road, La ...)
資料名： Bioorganic & Medicinal Chemistry Letters  (Bioorganic & Medicinal Chemistry Letters)
巻： 22  号： 21  ページ： 6656-6660  発行年： 2012年11月01日 
JST資料番号： W0248A  ISSN： 0960-894X  資料種別： 逐次刊行物 (A)
発行国： オランダ (NLD)  言語： 英語 (EN)

タイトルに関連する用語 (8件)： アペリン ,  APJ ,  受容体 ,  拮抗薬 ,  ピリミジン ,  4H-ピラン ,  4-ニトロベンゾアート ,  発見