文献

J-GLOBAL ID：201702238044888330   整理番号：17A0187826

ノルエピネフリンによるβ-アドレナリン受容体の活性化はヒトTHP-1細胞におけるERK/JNK-c-Fos経路を介してリポ多糖誘導マトリックスメタロプロテナーゼ-9発現を増強する

Beta-adrenoceptor Activation by Norepinephrine Enhances Lipopolysaccharide-induced Matrix Metalloproteinase-9 Expression Through the ERK/JNK-c-Fos Pathway in Human THP-1 Cells

著者 (9件)： Yin Xiang (Department of Cardiovascular Sciences, First Affiliated Hospital, School of Medicine, Zhejiang University) ,  Zhou Linli (Department of Cardiovascular Diseases, Shengzhou People’s Hospital) ,  Han Fei (Department of Cardiovascular Sciences, First Affiliated Hospital, School of Medicine, Zhejiang University) ,  Han Jie (Department of Cardiovascular Sciences, First Affiliated Hospital, School of Medicine, Zhejiang University) ,  Zhang Yuanyuan (Department of Cardiovascular Sciences, First Affiliated Hospital, School of Medicine, Zhejiang University) ,  Sun Zewei (Department of Cardiovascular Sciences, First Affiliated Hospital, School of Medicine, Zhejiang University) ,  Zhao Wenting (Department of Cardiovascular Sciences, First Affiliated Hospital, School of Medicine, Zhejiang University) ,  Wang Zhen (Department of Cardiovascular Sciences, First Affiliated Hospital, School of Medicine, Zhejiang University) ,  Zheng Liangrong (Department of Cardiovascular Sciences, First Affiliated Hospital, School of Medicine, Zhejiang University)
資料名： Journal of Atherosclerosis and Thrombosis (Web)  (Journal of Atherosclerosis and Thrombosis (Web))
巻： 24  号： 1  ページ： 55-67(J-STAGE)  発行年： 2017年 
JST資料番号： U0153A  ISSN： 1880-3873  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 目的:アテローム性動脈硬化症は慢性炎症性疾患であり,血栓症お...

シソーラス用語： ヒト ,...
準シソーラス用語： *マトリックスメタロプロテイナーゼ9 ,...

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著者キーワード (4件)： Norepinephrine ,  Lipopolysaccharide ,  Matrix metalloproteinase-9 ,  Atherosclerosis

分類 (2件)： 細胞生理一般  (EF02010S) ,  酵素生理  (EJ02020P)

物質索引 (1件)： ノルエピネフリン

引用文献 (30件)：

• 1) Shah PK, Falk E, Badimon JJ, Fernandez-Ortiz A, Mailhac A, Villareal-Levy G, Fallon JT, Regnstrom J, Fuster V. Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation 1995; 92: 1565-1569
• 2) Heo SH, Cho CH, Kim HO, Jo YH, Yoon KS, Lee JH, Park JC, Park KC, Ahn TB, Chung KC and others. Plaque rupture is a determinant of vascular events in carotid artery atherosclerotic disease: involvement of matrix metalloproteinases 2 and 9. J Clin Neurol 2011; 7: 69-76
• 3) De Paoli F, Eeckhoute J, Copin C, Vanhoutte J, Duhem C, Derudas B, Dubois-Chevalier J, Colin S, Zawadzki C, Jude B and others. The neuron-derived orphan receptor 1 (NOR1)is induced upon human alternative macrophage polarization and stimulates the expression of markers of the M2 phenotype. Atherosclerosis 2015; 241: 18-26
• 4) Stintzing S, Heuschmann P, Barbera L, Ocker M, Jung A, Kirchner T, Neureiter D. Overexpression of MMP9 and tissue factor in unstable carotid plaques associated with Chlamydia pneumoniae, inflammation, and apoptosis. Ann Vasc Surg 2005; 19: 310-319
• 5) Andoh Y, Ogura H, Satoh M, Shimano K, Okuno H, Fujii S, Ishimori N, Eshima K, Tamauchi H, Otani T and others. Natural killer T cells are required for lipopolysaccharide-mediated enhancement of atherosclerosis in apolipoprotein E-deficient mice. Immunobiology 2013; 218: 561-569

タイトルに関連する用語 (13件)： ノルエピネフリン ,  β-アドレナリン受容体 ,  活性化 ,  ヒト ,  THP-1細胞 ,  ERK ,  JNK ,  c-Fos ,  経路 ,  リポ多糖 ,  誘導 ,  発現 ,  増強