文献

J-GLOBAL ID：201702255330789485   整理番号：17A0036554

慢性C型肝炎に対するシメプレビル,ペグインターフェロン,およびリバビリン併用治療中のヘモグロビン低下に対するITPA多型の影響

Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C

著者 (25件)： Morio Kei (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Imamura Michio (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Kawakami Yoshiiku (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Morio Reona (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Hatooka Masahiro (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Kan Hiromi (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Fujino Hatsue (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Fukuhara Takayuki (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Kobayashi Tomoki (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Masaki Keiichi (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Ono Atsushi (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Nakahara Takashi (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Urabe Ayako (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Yokoyama Satoe (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Nagaoki Yuko (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Kawaoka Tomokazu (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Hiraga Nobuhiko (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Tsuge Masataka (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Hiramatsu Akira (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Hayes C Nelson (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Aikata Hiroshi (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Ochi Hidenori (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Ochi Hidenori (Laboratory for Digestive Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), Hiroshima, Japan) ,  Chayama Kazuaki (Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Chayama Kazuaki (Laboratory for Digestive Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), Hiroshima, Japan)
資料名： Hepatology Research  (Hepatology Research)
巻： 46  号： 12  ページ： 1256-1263  発行年： 2016年11月 
JST資料番号： W1284A  ISSN： 1386-6346  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オーストラリア (AUS)  言語： 英語 (EN)

抄録/ポイント： 目的:ITPA遺伝子における多型はペグインターフェロン(PE...

シソーラス用語： ヒト ,...
準シソーラス用語： *ITPA遺伝子 ,...

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著者キーワード (5件)： chronic hepatitis C ,  ITPA ,  simeprevir ,  ribavirin ,  hemoglobin

分類 (2件)： 消化器疾患の薬物療法  (GH05020G) ,  血液の疾患  (GK03000F)

物質索引 (2件)： シメプレビル ,  リバビリン

引用文献 (23件)：

• Kiyosawa K, Sodeyama T, Tanaka E et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 1990; 12: 671-5.
• Niederau C, Lange S, Heintges T et al. Prognosis of chronic hepatitis C: results of a large, prospective cohort study. Hepatology 1998; 28: 1687-95.
• Hadziyannis SJ, Sette H Jr, Morgan TR et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004; 140: 346-55.
• Chayama K, Hayes CN, Ohishi W et al. Treatment of chronic hepatitis C virus infection in Japan: update on therapy and guidelines. J Gastroenterol 2013; 48: 1-12.
• De Clercq E. Current race in the development of DAAs (directacting antivirals) against HCV. Biochem Pharmacol 2014; 89: 441-52.

タイトルに関連する用語 (7件)： 慢性C型肝炎 ,  シメプレビル ,  ペグインターフェロン ,  リバビリン ,  併用治療 ,  ヘモグロビン低下 ,  多型