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J-GLOBAL ID：201702279956741932   整理番号：17A0450259

グリカン官能化金ナノ粒子を用いたインフルエンザウイルスの検出と分化【Powered by NICT】

Detection and differentiation of influenza viruses with glycan-functionalized gold nanoparticles

著者 (28件)： Zheng Longtang (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Zheng Longtang (Savaid Medical School, University of Chinese Academy of Sciences, Huairou District, Beijing 101408, China) ,  Wei Jinhua (State Key Laboratory of Biochemical Engineering, PLA Key Laboratory of Biopharmaceutical Production & Formulation Engineering, Institute of Process Engineering, Chinese Academy of Sciences (CAS), Zhongguancun, Beijing 100190, China) ,  Lv Xun (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Bi Yuhai (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Bi Yuhai (Center for Influenza Research and Early-warning, Chinese Academy of Sciences (CASCIRE), Chaoyang District, Beijing 100101, China) ,  Wu Peixing (Lanzhou Institute of Animal Science and Veterinary Pharmaceutics, Chinese Academy of Agricultural Science, Lanzhou 730050, China) ,  Zhang Zhenxing (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Zhang Zhenxing (Savaid Medical School, University of Chinese Academy of Sciences, Huairou District, Beijing 101408, China) ,  Wang Pengfei (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Wang Pengfei (Savaid Medical School, University of Chinese Academy of Sciences, Huairou District, Beijing 101408, China) ,  Liu Ruichen (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Jiang Jingwen (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Jiang Jingwen (Savaid Medical School, University of Chinese Academy of Sciences, Huairou District, Beijing 101408, China) ,  Cong Haolong (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Liang Jingnan (Core Facility, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Chen Wenwen (CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Zhongguancun, Beijing 100190, China) ,  Cao Hongzhi (National Glycoengineering Research Center, School of Pharmaceutical Science, Shandong University, Jinan 250012, China) ,  Liu Wenjun (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Liu Wenjun (Center for Influenza Research and Early-warning, Chinese Academy of Sciences (CASCIRE), Chaoyang District, Beijing 100101, China) ,  Gao George F. (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Gao George F. (Center for Influenza Research and Early-warning, Chinese Academy of Sciences (CASCIRE), Chaoyang District, Beijing 100101, China) ,  Du Yuguang (State Key Laboratory of Biochemical Engineering, PLA Key Laboratory of Biopharmaceutical Production & Formulation Engineering, Institute of Process Engineering, Chinese Academy of Sciences (CAS), Zhongguancun, Beijing 100190, China) ,  Jiang Xingyu (CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Zhongguancun, Beijing 100190, China) ,  Li Xuebing (CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Chaoyang District, Beijing 100101, China) ,  Li Xuebing (National Engineering Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang 330022, China) ,  Li Xuebing (Savaid Medical School, University of Chinese Academy of Sciences, Huairou District, Beijing 101408, China) ,  Li Xuebing (Center for Influenza Research and Early-warning, Chinese Academy of Sciences (CASCIRE), Chaoyang District, Beijing 100101, China)
資料名： Biosensors & Bioelectronics  (Biosensors & Bioelectronics)
巻： 91  ページ： 46-52  発行年： 2017年 
JST資料番号： D0173C  ISSN： 0956-5663  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： インフルエンザウイルスの正確な診断は困難であり,一般的にはウイルス多様性および急速な変異性のために複雑なプロセスを必要とする。本研究では,グリカン官能化金ナノ粒子(gGNPs)を用いたインフルエンザウイルスの検出と鑑別のための単純かつ迅速な戦略を報告した。この方法はウイルス表面,グリカンへのウイルスの特異的結合により仲介されるにgGNPプローブの凝集に基づいている。異なるグリカン構造を有するgGNPsのセットを使用して,ヒトおよびトリ集団で循環している現在の主要なサブタイプを含む十四種のインフルエンザウイルス株は互いにと一段階比色法におけるヒト呼吸器合胞体ウイルスから分化した。ここに提示した結果は,インフルエンザウイルスの臨床診断とサーベイランスのための簡便で携帯型センサの開発におけるこのgGNPベースシステムの可能性を実証した。Copyright 2017 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： RSウイルス ,  高速度 ,  ヒト ,  *インフルエンザウイルス ,  サーベイランス ,  鑑別 ,  *官能化 ,  比色分析 ,  *ウイルス ,  携帯型 ,  プローブ
準シソーラス用語： 臨床診断 ,  サブタイプ ,  *金ナノ粒子 ,  *グリカン , 【Automatic Indexing@JST】

著者キーワード (5件)： 検出 ,  Differentiation ,  グリカン ,  金ナノ粒子 ,  インフルエンザウイルス

分類 (3件)： 生化学的分析法  (EA03030G) ,  微生物検査法  (EG02020G) ,  バイオアッセイ  (EA03060N)

タイトルに関連する用語 (5件)： グリカン ,  官能化 ,  金ナノ粒子 ,  インフルエンザウイルス ,  分化