JM Dijkstra

所属機関・部署：
職名：准教授
ホームページURL (1件)： http://kaken.nii.ac.jp/ja/r/10387681

研究分野 (3件)：免疫学 , 進化生物学 , 水圏生産科学

研究キーワード (20件)： Cytokines , MHC , Fish , Evolution , Immunology , 抗原提示 , 免疫システム , 原始的 , 獲得免疫 , MHC , 脊椎動物 , 分子ファミリー , 自然免疫 , 進化 , 分子進化 , 水産学 , 生体分子 , 免疫学 , 遺伝子 , ゲノム

競争的資金等の研究課題 (11件)：

2022 - 2024 Harnessing interleukin 2 (LI-2) family power in fish; Study of rainbow trout IL-2, IL-15, IL-15L, and IL- 15Rα
2021 - Assessing protective immunity to COVID19 provided by prior seasonal coronavirus infection
2016 - 2019 Harnessing interleukin 2 (LI-2) family power in fish; Study of rainbow trout IL-2, IL-15, IL-15L, and IL- 15Rα
2014 - 2018 主要組織適合遺伝子複合体(MHC)クラスII分子ペプチド積載機構の分子進化の解明
2012 - 2017 Targeted disease prophylaxis in European fish farming

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論文 (87件)：

Fumio Takizawa, Keiichiro Hashimoto, Ryuichiro Miyazawa, Yuko Ohta, Ana Veríssimo, Martin F. Flajnik, David Parra, Kotaro Tokunaga, Hiroaki Suetake, J. Oriol Sunyer, et al. CD4 and LAG-3 from sharks to humans: related molecules with motifs for opposing functions. Frontiers in Immunology. 2023. 14
Kazumasa Wakamatsu, Johannes M Dijkstra, Turid Mørkøre, Shosuke Ito. Eumelanin Detection in Melanized Focal Changes but Not in Red Focal Changes on Atlantic Salmon (Salmo salar) Fillets. International journal of molecular sciences. 2023. 24. 23
Takuma Asahi, Shinya Abe, Guangwei Cui, Akihiro Shimba, Tsukasa Nabekura, Hitoshi Miyachi, Satsuki Kitano, Keizo Ohira, Johannes M Dijkstra, Masaki Miyazaki, et al. Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches. eLife. 2023. 12
Peter Riederer, Toshiharu Nagatsu, Moussa B H Youdim, Max Wulf, Johannes M Dijkstra, Jeswinder Sian-Huelsmann. Lewy bodies, iron, inflammation and neuromelanin: pathological aspects underlying Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). 2023. 130. 5. 627-646
Yujiao Sun, Lizhen Ma, Shen Li, Yawen Wang, Ruiqi Xiao, Junqi Yang, Johannes M Dijkstra, Chun Xia. Crystal Structure of a Classical MHC Class I Molecule in Dogs; Comparison of DLA-88*0 and DLA-88*5 Category Molecules. Cells. 2023. 12. 7

講演・口頭発表等 (26件)：

The evolution of interleukins 2, 15, and 15-like, an ancient family of cytokines involved in lymphocyte activation
(Seminar, Institute for Life and Medical Sciences, Kyoto University 2022)
Deep Evolution of MHC Molecules
(Seminar at Institute of Immunology and Infection Research, University of Edinburgh, UK 2022)
The Evolution of Cytokines in Jawed Vertebrate Species
(Intensive Lecture Seminar (集中講義のセミナ), School of Science, Division of Biological Sciences, Nagoya University 2020)
The first functional characterization of ancient interleukin-15-like (IL-15L) reveals shared and distinct functions of the IL-2, -15 and -15L family cytokines
(第31回学術集会日本比較免疫学会 2019)
Evolution of the immune system
(Fish immunology seminar at the Laboratory of Fish Pathology, Department of Veterinary Medicine, Nihon University, Fujisawa, Kanagawa 2019)

学位 (1件)：

Ph.D. (Utrecht University, Holland)

経歴 (10件)：

2020/04 - 現在 Fujita Health University Research Promotion and Support Headquarters
2020/04 - 現在藤田医科大学総合医科学研究所准教授
2014 - 2020/03 藤田保健衛生大学総合医科学研究所医高分子学研究部門講師
2004 - 2014 , Fujita Health University, Institute for Comprehensive Medical Science, Division of Biomedical Polymer Science Assistant Professor
2008 - 2010 藤田保健衛生大学助教

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受賞 (3件)：

2022/05 - Editors of Toxins (MDPI) Editor's Choice Article Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen. Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T. Toxins (Basel). 2022 Mar 25;14(4):236. doi: 10.3390/toxins14040236.
2022/02 - PNAS Editors Paper selection for highlighting In This Issue (https://www.pnas.org/doi/10.1073/iti5121118) and Commentary article (doi: 10.1073/pnas.2122079119). Discovery of an ancient MHC category with both class I and class II features. Okamura K, Dijkstra JM, Tsukamoto K, Grimholt U, Wiegertjes GF, Kondow A, Yamaguchi H, Hashimoto K. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2108104118. doi: 10.1073/pnas.2108104118.
2021/08 - The Japanese Association for Developmental and Comparative Immunology Furuta Excellent Paper Award Ancient Cytokine Interleukin 15-Like (IL-15L) Induces a Type 2 Immune Response

所属学会 (4件)：

American Association for the Advancement of Science (AAAS) , The Molecular Biology Society of Japan (MBSJ) , The Japanese Association for Developmental & Comparative Immunology (JADCI) , Japanese Society for Immunology (JSI)

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