劉莉

リュウリ | Liu Li

所属機関・部署：
職名：特任教授

研究分野 (3件)：生体医工学 , 生体材料学 , 心臓血管外科学

競争的資金等の研究課題 (19件)：

2022 - 2031 フォトニクス生命工学研究開発拠点
2022 - 2025 心筋ー間葉系幹細胞複合型組織の構築及び虚血性心筋症への再生治療
2022 - 2025 創薬用複合型心筋組織電学機能評価システムの開発
2022 - 2025 心筋組織機能評価用新規デバイスを用いた医薬品安全・有効性評価
2020 - 2023 重症心不全を根治する“3D Mini Heart” 創成

全件表示

論文 (62件)：

Junjun Li, Ying Hua, Yuting Liu, Xiang Qu, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Hayato Miyoshi, Mikio Shiba, et al. Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessment. iScience. 2024. 27. 2. 108992-108992
Jingbo Zhang, Junjun Li, Xiang Qu, Yuting Liu, Akima Harada, Ying Hua, Noriko Yoshida, Masako Ishida, Akiko Tabata, Lifu Sun, et al. Development of a thick and functional human adipose-derived stem cell tissue sheet for myocardial infarction repair in rat hearts. Stem cell research & therapy. 2023. 14. 1. 380-380
Akihiro Hashida, Taro Nakazato, Toshimasa Uemura, Li Liu, Shigeru Miyagawa, Yoshiki Sawa, Masahiro Kino-oka. Effect of morphological change on the maturation of human induced pluripotent stem cell-derived cardiac tissue in rotating flow culture. Regenerative Therapy. 2023
Junjun Li, Xiang Qu, Li Liu, Lingjun Li, Ying Hua, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Nagako Sougawa, et al. Developing Thick Cardiac Tissue with a Multilayer Fiber Sheet for Treating Myocardial Infarction. Advanced Fiber Materials. 2023
Xiang Qu, Junjun Li, Li Liu, Jingbo Zhang, Ying Hua, Kota Suzuki, Akima Harada, Masako Ishida, Noriko Yoshida, Daisuke Okuzaki, et al. ONO-1301 enhances post-transplantation survival of human induced pluripotent stem cell-derived cardiac tissue sheet by promoting angiogenesis. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2023. 42. 6. 716-729

MISC (30件)：

Kazuhiro Aiba, Liu Li, Kensuke Kato, Norio Nakatsuji. SCAD-MT Cardiomyocyte: Human Pluripotent Stem Cell-Derived Cardiomyocyte Micro-tissues That Show Maturation and Functional Stability Promoted by Using Aligned Nanofibers. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017. 88. 235-235
劉莉. Low cell-matrix adhesion microenvironment promote maintain of high-pluripotency state stem cells. 10 Years of iPSCs Cell Symposium. 2016
劉莉. Engineered anisotropic and 3-demensional hiPS-derived cardiac tissue-like construct for drug assessment and cardiac disease repairing. 13th International Society for Stem Cell Research (ISSCR) Annual Meeting. 2016
劉莉. Creating functional anisotropic and 3D tissue-like construct using induced pluripotent stem cell-derived cardiomyocytes. CiRA/ISSCR 2016 International Symposia. 2016
劉莉. Controlling Maturation And Function Of Cardiomyocytes Derived From Human Pluripotent Stem Cells Using Aligned Nanofibers. 12th International Society for Stem Cell Research (ISSCR) Annual Meeting. 2015

特許 (19件)：

細胞の凝集体の製造方法、凝集体の集団、細胞の培養方法
人工心筋組織、その使用、及びその製造方法
多層重厚組織体、その製造方法及びその用途
細胞培養方法及びその装置
ラマン散乱を用いた心筋細胞の評価方法

書籍 (1件)：

Fabrication of Thick and Anisotropic Cardiac Tissue on Nanofibrous Substrate for Repairing Infarcted Myocardium
Humana, New York, NY

講演・口頭発表等 (15件)：

Human iPSC derived cardiac tissue matured by spontaneous traveling waves for improved drug assessment.
(American Heart Association Scientific Session,)
Micro-/Nanofibrous Matrices for pluripotent stem cell and cardiac tissue transplantation
(MU-OU joint Symposium 2021)
機能性iPS細胞由来心筋組織を用いた心不全再生医療法の開発
(第20回日本再生医療学会)
ナノファイバーを用いたヒトiPS細胞由来心筋組織の構築及び再生医療への応用
(第58回日本人工臓器学会 2020)
Circulating traveling waves enhance the maturation of hipsc-derived cardiomyocytes in self-organized tissue ring
(the 8th Meeting of the International Federation for Artificial Organs. 2019)

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