研究者
J-GLOBAL ID:201401089727002803
更新日: 2024年02月01日
NAMASIVAYAM Pandian Ganesh
Ganesh-pandian Namasivayam
所属機関・部署:
職名:
Junior Associate Professor and Principal Investigator
その他の所属(所属・部署名・職名) (3件):
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AO Research Institute, Switzerland
Honorary Visiting Scientist
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Rutgers University, USA
Visiting Professor
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NCBS-inStem, India
職名Honorary Visiting Scientist
ホームページURL (1件):
https://www.namasivayam.icems.kyoto-u.ac.jp/
研究分野 (4件):
ケミカルバイオロジー
, ゲノム生物学
, 生体材料学
, 生体医工学
研究キーワード (5件):
ナノテクノロジー
, エピジェネティクス
, 細胞リプログラミング
, Bio-inspired therapeutics
, 人工遺伝子スイッチ
競争的資金等の研究課題 (13件):
- 2021 - 2024 遺伝子ネットワークを制御する分子の開発と細胞への応用
- 2019 - 2022 心筋症関連ミトコンドリア・核内遺伝子の協奏的制御を可能にする人工転写因子の開発
- 2019 - 2022 ケミカルバイオロジーによるミトコンドリアDNAの複製抑制
- 2019 - 2020 変異ミトコンドリア遺伝子選択的転写抑制剤の開発
- 2019 - 人工エピジェネティックスイッチを用いた核・ミトコンドリア内における心筋症関連遺伝子の制御
- 2017 - 2019 3カ国間技術提携による転写因子様ナノ粒子の開発と関節軟骨再生の実現
- 2016 - 2018 ナノ粒子ベース人工転写因子を用いた弓矢リプログラミング法による心筋細胞の誘導
- 2017 - 2017 細胞エネルギアクチベーターの抗肥満作用を有する自然に倣ったスマート転写因子の開発
- 2012 - 2017 分子科学的アプローチによる遺伝子発現の制御と機構の解明
- 2014 - 2015 Next-generation transcriptional activators for direct differentiation
- 2014 - 2015 治療に有効な遺伝子を制御する自然を模倣した革新的小分子化合物
- 2012 - 2014 多能性に関する転写機構をオンにするプログラム可能な小分子の開発
- 2011 - 2012 Development of artificial genetic switches.
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論文 (104件):
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Dan Bai, Reihane Ziadlou, Thangavel Vaijayanthi, Subramani Karthikeyan, Shanmugavel Chinnathambi, Anutthaman Parthasarathy, Li Cai, Marie-Charlotte Brüggen, Hiroshi Sugiyama, Ganesh N. Pandian. Nucleic acid-based small molecules as targeted transcription therapeutics for immunoregulation. Allergy. 2023
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Thangavel Vaijayanthi, Ganesh N. Pandian, Hiroshi Sugiyama. Pyrrole-Imidazole Polyamides - A Frontrunner in Nucleic Acid-Based Small Molecule Drugs. Advanced Therapeutics. 2023
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Rupavarshini, M., Karthikeyan, S., An, h, S., Ramamoorthi, A., Ramakrishnamurthy, S., Bharanidharan, G., Aruna, P., Mangaiyarkarasi, R., Chinnathambi, S., et al. A biophysical approach of cytarabine anticancer drug insights into human serum albumin and checkpoint kinase 1. Results in Chemistry. 2023. 5
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Vinodh J. Sahayasheela, Zutao Yu, Takuya Hidaka, Ganesh N. Pandian, Hiroshi Sugiyama. Mitochondria and G-quadruplex evolution: an intertwined relationship. Trends in Genetics. 2023. 39. 1. 15-30
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Seithikurippu R. Pandi-Perumal, Velayudhan Mohan Kumar, Namasivayam Ganesh Pandian, Joop T. de Jong, Sudalaikannu Andiappan, Alexandru Corlateanu, Arehally Marappa Mahalaksmi, Saravana Babu Chidambaram, Ramasamy Rajesh Kumar, Chellamuthu Ramasubramanian, et al. Scientists Against War: A Plea to World Leaders for Better Governance. Sleep and Vigilance. 2022. 6. 1
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書籍 (4件):
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Sequence-specific control of mitochondrial gene transcription using programmable synthetic gene switches called MITO-PIPs
Methods in Molecular Biology, Springer Protocols. Mitochondrial Medicine, 2nd edition, V. Weissig, M. Edeas, Editors. Humana Press, Springer New York Heidelberg Dordrecht London 2020
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Synthetic strategies to identify and regulate noncoding RNAs in LONG NONCODING RNAs: Structures and Functions
Springer Japan 2015
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Targeted editing of therapeutic genes using DNA-based transcriptional activators: Scope and Challenges in Chemical Biology of Nucleic Acids
Springer Berlin Heidelberg 2014
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Designing biomimicking synthetic transcription factors for therapeutic gene modulation
Springer
講演・口頭発表等 (21件):
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Programming synthetic molecular codes for bioengineering
(The Korean Society of Biotechnology and Bioengineering 2018)
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Designer molecule to target and silence mitochondrial gene transcription
(8th World congress on Targeting Mitochondria, , Berlin Berlin 2017)
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Nature-inspired smart genetic switches,
(7th Indian JSPS Alumni Association (IJAA) International Conference on Science and Technology: Future Challenges and Solutions (STFCS-2016) 2016)
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Therapeutic gene modulation using DNA-based transcriptional activators
(Asian International Symposium -Medicinal Chemistry in The 95th Annual Meeting of The Chemical Society of Japan 2015)
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Therapeutic gene modulation using DNA-based transcriptional activators,
(Asian International Symposium -Medicinal Chemistry in The 95th Annual Meeting of The Chemical Society of Japan 2015)
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学歴 (3件):
- 2006 - 2009 新潟大学 応用生物科学科 博士後期課程
- 2000 - 2002 University of Madras, India Biotechnology 修士課程(科学)
- 1997 - 2000 University of Madras, India Biochemistry 学士(科学)
学位 (3件):
- Ph.D (Applied Biosciences)
- Master of Science (Biotechnology)
- Bachelor of Science (Biochemistry)
経歴 (12件):
- 2018/10 - 現在 Rutgers University, 米国 KiBum Lab 客員研究員
- 2018/08 - 現在 Kyoto University iCeMS 主任研究者
- 2018/07 - 現在 京都大学 iCeMS 講師(終身雇用)
- 2018/03 - 現在 AO Research Institute, スイス Department of Musculoskeletal Regeneration 客員研究員
- 2016/03 - 2018/06 京都大学 iCeMS 助教(終身雇用)
- 2014/03 - 2016/02 Kyoto University iCeMS Program-Specific Research Center Assistant Professor
- 2010/01 - 2014/02 Kyoto University iCeMS Research Associate
- 2009/04 - 2010/01 Niigata University Hori Lab, Division of Applied Biosciences Research Assistant Professor
- 2009/10 - 2009/12 Ushiki and Associates Patent Office Niigata Office Visiting Scientific Advisor
- 2003/10 - 2006/01 Indian Institute of Technology-Madras (IIT-M) Department of Biotechnology Project Associate
- 2004/11 - 2005/10 Kelvin Chemicsls Chennai Branch Visiting Scientist
- 2002/06 - 2003/10 Indian Institute of Technology-Madras (IIT-M) Department of Chemistry Research Assistant
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委員歴 (4件):
- 2019/04 - 現在 Sub-member Asian Chemical Biology Initiative
- 2017/09 - 現在 World Mitochondria Society
- 2017/04 - 現在 KINKA CHEMICAL SOCIETY
- 2011/10 - 現在 Nucleic Acids Chemistry
受賞 (12件):
- 2021/08 - ACE International, Singapore INSPIRE Award
- 2020/04 - NBC India Lockdown Legend - Science Awareness
- 2018/06 - TEDx TEDx Kyoto University Speaker
- 2017/10 - 8th World Congress on Targeting Mitochondria Research Excellence Keynote Speaker
- 2017/08 - Brilliant Publishing Organization Rising Star Award-Science
- 2016/08 - Department of Biotechnology Program, DG Vaishnav College Scientist of the Month
- 2015/10 - iCeMS Kyoto University Make a Project Award
- 2013/03 - Royal Society of Chemistry (RSC) Biomaterials Poster Award - 1st Rank
- 2012/08 - iCeMS Kyoto University Cross-disciplinary research prize
- 2011/06 - Heidelberg-Kyoto Joint Symposium -2011 Best Poster Award and Biotechnology Journal Prize
- 2010/10 - iCeMS Kyoto University Best Poster and Excellence Award
- AAAS Science Translational Medicine and Days of Molecular Medicine-2011 Young Investigator Award
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