菊地逸平

キクチイッペイ | Kikuchi Ippei

所属機関・部署：
職名：上級研究員

研究分野 (3件)：細胞生物学 , 分子生物学 , 腫瘍生物学

研究キーワード (6件)：ゲノム編集 , リン酸化 , シグナル伝達 , チロシンホスファターゼ , チロシンキナーゼ , がん

競争的資金等の研究課題 (6件)：

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論文 (7件)：

Ippei Kikuchi, Yusuke Iwashita, Atsushi Takahashi-Kanemitsu, Michinori Koebis, Atsu Aiba, Masanori Hatakeyama. Coevolution of the ileum with Brk/Ptk6 family kinases confers robustness to ileal homeostasis. Biochemical and Biophysical Research Communications. 2023
Atsushi Takahashi-Kanemitsu, Mengxue Lu, Christopher Takaya Knight, Takayoshi Yamamoto, Takuo Hayashi, Yusuke Mii, Takuya Ooki, Ippei Kikuchi, Akira Kikuchi, Nick Barker, et al. The Helicobacter pylori CagA oncoprotein disrupts Wnt/PCP signaling and promotes hyperproliferation of pyloric gland base cells. Science Signaling. 2023. 16. 794. eabp9020
Tang C, Takahashi-Kanemitsu A, Kikuchi I, Ben C, Hatakeyama M. Transcriptional Co-activator Functions of YAP and TAZ Are Inversely Regulated by Tyrosine Phosphorylation Status of Parafibromin. iScience. 2018. 1. 1. 1-15
Ippei Kikuchi, Atsushi Takahashi-Kanemitsu, Natsuki Sakiyama, Chao Tang, Pei-Jung Tang, Saori Noda, Kazuki Nakao, Hidetoshi Kassai, Toshiro Sato, Atsu Aiba, et al. Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways. Nature Communications. 2016. 7. 12887
Ryouhei Tsutsumi, Mohammad Masoudi, Atsushi Takahashi, Yumiko Fujii, Takeru Hayashi, Ippei Kikuchi, Yumeko Satou, Masanori Taira, Masanori Hatakeyama. YAP and TAZ, Hippo Signaling Targets, Act as a Rheostat for Nuclear SHP2 Function. Developmental Cell. 2013. 26. 6. 658-665

講演・口頭発表等 (10件)：

Ptk6 family kinases play a specific role in the maintenance of ileal mucosal homeostasis in the alimentary tract
(12th AACR-JCA Joint Conference 2022)
Inverse control of transcription co-activator function of YAP and TAZ by tyrosine phosphorylation status of Parafibromin
(The 77th Annual Meeting of the Japanese Cancer Association 2018)
Parafibromin acts as a transcriptional scaffold protein that integrates multiple morphogen signaling pathways
(第37回札幌がんセミナー国際シンポジウム 2018)
Transcriptional co-activator function of YAP/TAZ are inversely regulated by phosphorylation status of Parafibromin
(The 37th Sapporo International Cancer Symposium. 2018)
Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways(第9回日本プロテインホスファターゼ研究会賞受賞講演)
(平成29年度日本プロテインホスファターゼ研究会学術集会 2017)

学位 (1件)：

経歴 (7件)：

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受賞 (2件)：

所属学会 (1件)：

日本癌学会

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菊地 逸平