文献
J-GLOBAL ID:201502265789220762
整理番号:15A0510056
がん:MLL遺伝子再構成を伴う白血病で,DOT1LはSIRT1を介したエピジェネティックなサイレンシングを抑制して白血病遺伝子の発現を維持する
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
著者 (19件):
CHEN Chun-Wei
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
KOCHE Richard P
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
SINHA Amit U
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
DESHPANDE Aniruddha J
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
ZHU Nan
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
ENG Rowena
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
XU Haiming
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
CHU Scott H
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
WANG Xi
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
DELANEY Christopher
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
ARMSTRONG Scott A
(Memorial Sloan Kettering Cancer Center, New York, USA)
,
DOENCH John G
(Broad Inst. of Massachusetts Inst. of Technol. and Harvard, Massachusetts, USA)
,
ROOT David E
(Broad Inst. of Massachusetts Inst. of Technol. and Harvard, Massachusetts, USA)
,
HAHN William C
(Broad Inst. of Massachusetts Inst. of Technol. and Harvard, Massachusetts, USA)
,
BRADNER James E
(Broad Inst. of Massachusetts Inst. of Technol. and Harvard, Massachusetts, USA)
,
QI Jun
(Dana-Farber Cancer Inst., Massachusetts, USA)
,
HAHN William C
(Dana-Farber Cancer Inst., Massachusetts, USA)
,
BRADNER James E
(Dana-Farber Cancer Inst., Massachusetts, USA)
,
BERNT Kathrin M
(Univ. Colorado School of Medicine, Colorado, USA)
資料名:
Nature Medicine
(Nature Medicine)
巻:
21
号:
4
ページ:
335-343
発行年:
2015年04月
JST資料番号:
W0636A
ISSN:
1078-8956
資料種別:
逐次刊行物 (A)
記事区分:
原著論文
発行国:
アメリカ合衆国 (USA)
言語:
英語 (EN)