文献
J-GLOBAL ID:201702281247652680
整理番号:17A1714301
足場ホッピングによる新規2,4-ジメチルキノリン-6-カルボアミドM_4陽性アロステリックモジュレーター(PAM)ケモタイプの発見【Powered by NICT】
Discovery of a novel 2,4-dimethylquinoline-6-carboxamide M4 positive allosteric modulator (PAM) chemotype via scaffold hopping
著者 (29件):
Long Madeline F.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Long Madeline F.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Engers Julie L.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Engers Julie L.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Chang Sichen
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Chang Sichen
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Zhan Xiaoyan
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Zhan Xiaoyan
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Weiner Rebecca L.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Weiner Rebecca L.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Luscombe Vincent B.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Luscombe Vincent B.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Rodriguez Alice L.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Rodriguez Alice L.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Cho Hyekyung P.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Cho Hyekyung P.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Niswender Colleen M.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Niswender Colleen M.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Niswender Colleen M.
(Vanderbilt Kennedy Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Bridges Thomas M.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Bridges Thomas M.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Conn P. Jeffrey
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Conn P. Jeffrey
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Conn P. Jeffrey
(Vanderbilt Kennedy Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Engers Darren W.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Engers Darren W.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Lindsley Craig W.
(Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA)
,
Lindsley Craig W.
(Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA)
,
Lindsley Craig W.
(Department of Chemistry, Vanderbilt University, Nashville, TN 37232, USA)
資料名:
Bioorganic & Medicinal Chemistry Letters
(Bioorganic & Medicinal Chemistry Letters)
巻:
27
号:
22
ページ:
4999-5001
発行年:
2017年
JST資料番号:
W0248A
ISSN:
0960-894X
資料種別:
逐次刊行物 (A)
記事区分:
原著論文
発行国:
オランダ (NLD)
言語:
英語 (EN)