文献
J-GLOBAL ID:201802291186804093
整理番号:18A0509763
リウマチ関節炎の治療のための改良された薬物動態学的特性を有する選択的Btk阻害剤として7H-ピロロ[2,3-d]ピリミジン-4-アミン誘導体の設計,合成および生物学的評価【Powered by NICT】
Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as selective Btk inhibitors with improved pharmacokinetic properties for the treatment of rheumatoid arthritis
著者 (10件):
He Linhong
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
,
Pei Heying
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
,
Zhang Chufeng
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
,
Shao Mingfeng
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
,
Li Dan
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
,
Tang Mingli
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
,
Wang Taijing
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
,
Chen Xiaoxin
(Guangdong Zhongsheng Pharmaceutical Co., Ltd., Dongguan, Guangdong 523325, China)
,
Xiang Mingli
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
,
Chen Lijuan
(State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China)
資料名:
European Journal of Medicinal Chemistry
(European Journal of Medicinal Chemistry)
巻:
145
ページ:
96-112
発行年:
2018年
JST資料番号:
E0845A
ISSN:
0223-5234
資料種別:
逐次刊行物 (A)
記事区分:
原著論文
発行国:
オランダ (NLD)
言語:
英語 (EN)