文献
J-GLOBAL ID:201902283100711815
整理番号:19A1562974
パゾパニブは活性代謝物SN-38のUGT1A1仲介グルクロン酸化を阻害するが,OATP1B1介在性肝取り込みを阻害することによりイリノテカンと相互作用する【JST・京大機械翻訳】
Pazopanib interacts with irinotecan by inhibiting UGT1A1-mediated glucuronidation, but not OATP1B1-mediated hepatic uptake, of an active metabolite SN-38
著者 (9件):
Iwase Mariko
(Department of Pharmacology, Showa University School of Medicine, Tokyo, Japan)
,
Fujita Ken-ichi
(Institute of Molecular Oncology, Showa University, Tokyo, Japan)
,
Fujita Ken-ichi
(Division of Cancer Cell Biology, Department of Pharmaceutical Science, Showa University School of Pharmacy, Tokyo, Japan)
,
Nishimura Yuki
(Department of Pharmacology, Showa University School of Medicine, Tokyo, Japan)
,
Seba Natsumi
(Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan)
,
Masuo Yusuke
(Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan)
,
Ishida Hiroo
(Division of Medical Oncology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan)
,
Kato Yukio
(Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan)
,
Kiuchi Yuji
(Department of Pharmacology, Showa University School of Medicine, Tokyo, Japan)
資料名:
Cancer Chemotherapy and Pharmacology
(Cancer Chemotherapy and Pharmacology)
巻:
83
号:
5
ページ:
993-998
発行年:
2019年
JST資料番号:
W4134A
ISSN:
1432-0843
資料種別:
逐次刊行物 (A)
記事区分:
短報
発行国:
ドイツ (DEU)
言語:
英語 (EN)