文献
J-GLOBAL ID:201902292958222462
整理番号:19A1406972
R-spineとの干渉による優れた選択性,高い効力および長期標的滞留時間を有する新規I型1/2p38α MAPキナーゼ阻害剤の設計,合成および生物学的評価【JST・京大機械翻訳】
Design, Synthesis, and Biological Evaluation of Novel Type I1/2 p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine
著者 (13件):
Walter Niklas M.
(Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universitaet Tuebingen, Germany)
,
Wentsch Heike K.
(Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universitaet Tuebingen, Germany)
,
Buehrmann Mike
(Faculty of Chemistry and Chemical Biology, Technische Universitaet Dortmund, Germany)
,
Bauer Silke M.
(Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universitaet Tuebingen, Germany)
,
Doering Eva
(Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universitaet Tuebingen, Germany)
,
Mayer-Wrangowski Svenja
(Faculty of Chemistry and Chemical Biology, Technische Universitaet Dortmund, Germany)
,
Sievers-Engler Adrian
(Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universitaet Tuebingen, Germany)
,
Willemsen-Seegers Nicole
(Netherlands Translational Research Center B.V. (NTRC), The Netherlands)
,
Zaman Guido
(Netherlands Translational Research Center B.V. (NTRC), The Netherlands)
,
Buijsman Rogier
(Netherlands Translational Research Center B.V. (NTRC), The Netherlands)
,
Laemmerhofer Michael
(Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universitaet Tuebingen, Germany)
,
Rauh Daniel
(Faculty of Chemistry and Chemical Biology, Technische Universitaet Dortmund, Germany)
,
Laufer Stefan A.
(Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universitaet Tuebingen, Germany)
資料名:
Journal of Medicinal Chemistry
(Journal of Medicinal Chemistry)
巻:
60
号:
19
ページ:
8027-8054
発行年:
2017年10月12日
JST資料番号:
D0102A
ISSN:
0022-2623
CODEN:
JMCMAR
資料種別:
逐次刊行物 (A)
記事区分:
原著論文
発行国:
アメリカ合衆国 (USA)
言語:
英語 (EN)