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J-GLOBAL ID：202002261645213415 整理番号：20A2453913

疾患関連SHP2変異体の相分離はMAPK過活性化の基礎をなす【JST・京大機械翻訳】

Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation

著者 (34件)：

Zhu Guangya

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Zhu Guangya

(University of the Chinese Academy of Sciences, Beijing 100049, China)

Xie Jingjing

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Xie Jingjing

(University of the Chinese Academy of Sciences, Beijing 100049, China)

Kong Wenna

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Kong Wenna

(University of the Chinese Academy of Sciences, Beijing 100049, China)

Xie Jingfei

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Xie Jingfei

(University of the Chinese Academy of Sciences, Beijing 100049, China)

Li Yichen

(Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, China)

Du Lin

(Etern Biopharma Co. Ltd., Shanghai 201203, China)

Zheng Qiangang

(Etern Biopharma Co. Ltd., Shanghai 201203, China)

Sun Lin

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Guan Mingfeng

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Guan Mingfeng

(University of the Chinese Academy of Sciences, Beijing 100049, China)

Li Huan

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Li Huan

(University of the Chinese Academy of Sciences, Beijing 100049, China)

Zhu Tianxin

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Zhu Tianxin

(University of the Chinese Academy of Sciences, Beijing 100049, China)

He Hao

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

He Hao

(University of the Chinese Academy of Sciences, Beijing 100049, China)

Liu Zhenying

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Liu Zhenying

(University of the Chinese Academy of Sciences, Beijing 100049, China)

Xia Xi

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Kan Chen

(Department of Pathophysiology, Anhui Medical University, Hefei 230032, China)

Tao Youqi

(Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, China)

Shen Hong C.

(Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Shanghai 201203, China)

Li Dan

(Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, China)

Wang Siying

(Department of Pathophysiology, Anhui Medical University, Hefei 230032, China)

Yu Yongguo

(Department of Pediatric Endocrinology and Genetics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute for Pediatric Research, Shanghai 200092, China)

Yu Zhi-Hong

(Department of Medicinal Chemistry and Molecular Pharmacology, Center for Cancer Research and Institute for Drug Discovery, Purdue University, West Lafayette, IN 47907, USA)

Zhang Zhong-Yin

(Department of Medicinal Chemistry and Molecular Pharmacology, Center for Cancer Research and Institute for Drug Discovery, Purdue University, West Lafayette, IN 47907, USA)

Liu Cong

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Zhu Jidong

(Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China)

Zhu Jidong

(Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China)

資料名：

Cell (Cambridge, Mass.) (Cell (Cambridge, Mass.))

巻： 183 号： 2 ページ： 490-502.e18 発行年： 2020年
JST資料番号： A0707B ISSN： 0092-8674 資料種別：逐次刊行物 (A)
記事区分：原著論文発行国：アメリカ合衆国 (USA) 言語：英語 (EN)

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