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J-GLOBAL ID:202002265377739871   整理番号:20A0896882

リスク予測:67万6000人に対するバイオバンク横断解析で明らかになった,複雑形質の多遺伝子性リスクスコアとヒト寿命との関連

Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan
著者 (36件):
SAKAUE Saori
(Lab. for Statistical Analysis, RIKEN Center for Integrative Medical Sci., Yokohama, JPN)
KANAI Masahiro
(Lab. for Statistical Analysis, RIKEN Center for Integrative Medical Sci., Yokohama, JPN)
AKIYAMA Masato
(Lab. for Statistical Analysis, RIKEN Center for Integrative Medical Sci., Yokohama, JPN)
MATOBA Nana
(Lab. for Statistical Analysis, RIKEN Center for Integrative Medical Sci., Yokohama, JPN)
TAKAHASHI Atsushi
(Lab. for Statistical Analysis, RIKEN Center for Integrative Medical Sci., Yokohama, JPN)
KAMATANI Yoichiro
(Lab. for Statistical Analysis, RIKEN Center for Integrative Medical Sci., Yokohama, JPN)
SAKAUE Saori
(Dep. of Statistical Genetics, Osaka Univ. Graduate School of Medicine, Suita, JPN)
KANAI Masahiro
(Dep. of Statistical Genetics, Osaka Univ. Graduate School of Medicine, Suita, JPN)
OKADA Yukinori
(Dep. of Statistical Genetics, Osaka Univ. Graduate School of Medicine, Suita, JPN)
SAKAUE Saori
(Dep. of Allergy and Rheumatology, Graduate School of Medicine, Univ. Tokyo, Tokyo, JPN)
KANAI Masahiro
(Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA)
KARJALAINEN Juha
(Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA)
KURKI Mitja
(Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA)
DALY Mark J.
(Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA)
KANAI Masahiro
(Program in Medical and Population Genetics, Broad Inst. of Harvard and MIT, Cambridge, MA, USA)
KARJALAINEN Juha
(Program in Medical and Population Genetics, Broad Inst. of Harvard and MIT, Cambridge, MA, USA)
KURKI Mitja
(Program in Medical and Population Genetics, Broad Inst. of Harvard and MIT, Cambridge, MA, USA)
DALY Mark J.
(Program in Medical and Population Genetics, Broad Inst. of Harvard and MIT, Cambridge, MA, USA)
KANAI Masahiro
(Stanley Center for Psychiatric Res., Broad Inst. of Harvard and MIT, Cambridge, MA, USA)
KARJALAINEN Juha
(Stanley Center for Psychiatric Res., Broad Inst. of Harvard and MIT, Cambridge, MA, USA)
KURKI Mitja
(Stanley Center for Psychiatric Res., Broad Inst. of Harvard and MIT, Cambridge, MA, USA)
DALY Mark J.
(Stanley Center for Psychiatric Res., Broad Inst. of Harvard and MIT, Cambridge, MA, USA)
KANAI Masahiro
(Dep. of Biomedical Informatics, Harvard Medical School, Boston, MA, USA)
KANAI Masahiro
(Inst. for Molecular Medicine Finland (FIMM), Univ. Helsinki, Helsinki, FIN)
KARJALAINEN Juha
(Inst. for Molecular Medicine Finland (FIMM), Univ. Helsinki, Helsinki, FIN)
KURKI Mitja
(Inst. for Molecular Medicine Finland (FIMM), Univ. Helsinki, Helsinki, FIN)
DALY Mark J.
(Inst. for Molecular Medicine Finland (FIMM), Univ. Helsinki, Helsinki, FIN)
AKIYAMA Masato
(Dep. of Ophthalmology, Graduate School of Medical Sci., Kyushu Univ., Fukuoka, Fukuoka, JPN)
TAKAHASHI Atsushi
(Dep. of Genomic Medicine, Res. Inst., National Cerebral and Cardiovascular Center, Suita, JPN)
HIRATA Makoto
(Lab. of Genome Technol., Inst. of Medical Sci., Univ. Tokyo, Tokyo, JPN)
KUBO Michiaki
(RIKEN Center for Integrative Medical Sci., Yokohama, JPN)
MATSUDA Koichi
(Dep. of Computational Biology and Medical Sci., Graduate School of Frontier Sci., Univ. Tokyo, Tokyo, JPN)
MURAKAMI Yoshinori
(Div. of Molecular Pathology, Inst. of Medical Sci., Univ. Tokyo, Tokyo, JPN)
KAMATANI Yoichiro
(Lab. of Complex Trait Genomics, Dep. of Computational Biology and Medical Sci., Graduate School of Frontier Sci., Univ. Tokyo, Tokyo, JPN)
OKADA Yukinori
(Lab. of Statistical Immunology, Immunology Frontier Res. Center (WPI-IFReC), Osaka Univ., Suita, JPN)
OKADA Yukinori
(Integrated Frontier Res. for Medical Sci. Div., Inst. for Open and Transdisciplinary Res. Initiatives, Osaka Univ., Suita, JPN)

資料名:
Nature Medicine  (Nature Medicine)

巻: 26  号:ページ: 542-548  発行年: 2020年04月 
JST資料番号: W0636A  ISSN: 1078-8956  資料種別: 逐次刊行物 (A)
記事区分: 原著論文  発行国: アメリカ合衆国 (USA)  言語: 英語 (EN)
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