研究キーワード (7件):
がん治療
, リポソーム
, 抗癌剤
, 核酸医薬品
, 葉酸修飾
, 薬物送達システム
, Drug delivery system
競争的資金等の研究課題 (5件):
2014 - 2017 イオン液体を利用した遺伝子リポプレックスの固形製剤化に関する研究
2007 - 2009 膜透過性ペプチド修飾抗がん剤封入脂質微粒子製剤の開発
2004 - 2005 腫瘍選択的薬物送達を目的とした葉酸修飾抗がん剤封入微粒子製剤の開発
抗がん剤封入微粒子製剤の開発
腫瘍選択的薬物送達
論文 (68件):
Andang Miatmoko, Devy Maulidya Cahyani, Kumi Kawano, Yoshiyuki Hattori. Comparative cellular and in vivo anti-cancer studies of doxorubicin liposomes prepared with different types of phospholipids. Indonesian Journal of Pharmacy. 2024. 35. 3. 459-466
Yoshiyuki Hattori, Min Tang, Junnosuke Sato, Makoto Tsuiji, Kumi Kawano. Evaluation of mRNA lipoplexes prepared using modified ethanol injection method as a tumor vaccine. Journal of drug targeting. 2024. 1-17
Kumi Kawano, Ayami Furuya, Yuri Matsuda, Chisato Kimura, Kotono Yamaguchi, Sakura Wakabayashi, Kotone Taniguchi, Kei-ichi Ozaki, Yoshiyuki Hattori. Preparation of liposomes co-encapsulating doxorubicin and mifepristone for treating multidrug-resistant cancer. Journal of Drug Delivery Science and Technology. 2023. 104605-104605
Min Tang, Sho Sakasai, Hiraku Onishi, Kumi Kawano, Yoshiyuki Hattori. Effect of PEG anchor in PEGylation of folate-modified cationic liposomes with PEG-derivatives on systemic siRNA delivery into the tumor. Journal of Drug Targeting. 2023. 31. 1. 74-88