2004 - 2006 1) Gene therapy for Acute / chronic ischemic myocardium using platelet-derived endothelial cell growth factor/ Thymidine phosphorylase; 2) Gene therapy for vascular obstructive disease using platelet-derived endothelial cell growth factor/ Thymidine p・・・
1997 - 虚血性心疾患に対する血管新生の遺伝子治療
虚血性疾患に対する遺伝子治療法の開発
MISC (8件):
Li W, Tanaka K, Morioka K, Uesaka T, Yamada N, Takamori A, Handa M, Tanabe S, Ihaya A.Thymidine phosphorylase gene transfer inhibits vascular smooth muscle cell proliferation by upregulating heme oxygenase-1 and p27KIP1. Arterioscler Thromb Vasc Biol. 2005. 25(7):1370-5
Li W, Tanaka K, Ihaya A, Fujibayashi Y, Takamatsu S, Morioka K, Sasaki M, Uesaka T, Kimura T, Yamada N, Tsuda T, Chiba Y. Gene Therapy for Chronic Myocardial Ischemia Using Platelet-derived Endothelial Cell Growth Factor in Dogs. Am J Physiol Heart Circ Physiol. 2005. 288(1):H408-15
Li W, Tanaka K, Morioka K, Uesaka T, Yamada N, Takamori A, Handa M, Tanabe S, Ihaya A.Thymidine phosphorylase gene transfer inhibits vascular smooth muscle cell proliferation by upregulating heme oxygenase-1 and p27KIP1. Arterioscler Thromb Vasc Biol. 2005. 25(7):1370-5
Li W, Tanaka K, Ihaya A, Fujibayashi Y, Takamatsu S, Morioka K, Sasaki M, Uesaka T, Kimura T, Yamada N, Tsuda T, Chiba Y. Gene Therapy for Chronic Myocardial Ischemia Using Platelet-derived Endothelial Cell Growth Factor in Dogs. Am J Physiol Heart Circ Physiol. 2005. 288(1):H408-15
Li W, Tanaka K, Chiba Y, Kimura T, Morioka K, Uesaka T, Ihaya A, Sasaki M, Tsuda T, Yamada N. Role of MMPs and plasminogen activators in angiogenesis after transmyocardial laser revascularization in dogs. Am J Physiol Heart Circ Physiol. 2003. 284:H23-H30