大島正伸

Oshima Masanobu

ホームページURL (1件)： http://genetics.w3.kanazawa-u.ac.jp

研究キーワード (3件)： mouse model , genetics , inflammation and cancer

競争的資金等の研究課題 (36件)：

全件表示

論文 (170件)：

Hiroshi Kotani, Hiroko Oshima, Justin C Boucher, Tomoyoshi Yamano, Hiroyuki Sakaguchi, Shigeki Sato, Koji Fukuda, Akihiro Nishiyama, Kaname Yamashita, Koushiro Ohtsubo, et al. Dual inhibition of SUMOylation and MEK conquers MYC-expressing KRAS-mutant cancers by accumulating DNA damage. Journal of biomedical science. 2024. 31. 1. 68-68
Dong Wang, Emily Woodcock, Xi Yang, Hiromi Nishikawa, Elena V. Sviderskaya, Masanobu Oshima, Christopher Edwards, Yanjun Zhang, Yuri Korchev. Exploration of individual colorectal cancer cell responses to H2O2 eustress using hopping probe scanning ion conductance microscopy. Science Bulletin. 2024. 69. 12. 1909-1919
Masahiro Hashimoto, Yasuhiro Kojima, Takeharu Sakamoto, Yuki Ozato, Yusuke Nakano, Tadashi Abe, Kiyotaka Hosoda, Hideyuki Saito, Satoshi Higuchi, Yuichi Hisamatsu, et al. Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis. EBioMedicine. 2024. 103. 105102-105102
Yukinori Ikeda, Jun-ichi Suehiro, Hiroko Oshima, Sau Yee Kok, Kazuki Takahashi, Hiroyuki Sakurai, Tetsuro Watabe, Masanobu Oshima, Yukiko T. Matsunaga. Tumor-microvessel on-a-chip reveals sequential intravasation cascade of cancer cell clusters. bioRxiv. 2024
Spatiotemporal observation reveals metastatic tumor-driven vascular remodeling as a potential route to polyclonal colonization. bioRxiv. 2024

MISC (80件)：

Hiroki Sato, Ryu Imamura, Katsuya Sakai, Hiroko Oshima, Masanobu Oshima, Kazuhiro Murakami, Yumi Terakado, Yukinari Kato, Seiji Yano, Kunio Matsumoto. Roles of Mature HGF in Gastric Tissue Regeneration and Tumorigenesis. CANCER SCIENCE. 2021. 112. 422-422
大木理恵子, 大塚旬子, 大島浩子, 安部良, 大島正伸. がん抑制遺伝子p53機能喪失とがん微小環境は協調的に胃がん悪性化を促進する(Functional loss of p53 cooperates with the in vivo microenvironment to promote malignant progression of gastric cancers). 日本癌学会総会記事. 2018. 77回. 1074-1074
寺門侑美, 村上和弘, 大島正伸, 大島浩子, Nick Barker. 胃がん幹細胞の検討とその制御機構(Analysis of gastric cancer stem cells and regulatory mechanism). 日本癌学会総会記事. 2018. 77回. 2098-2098
Donghui Cao, Jing Jiang, Dan Zhao, Menghui Wu, Houjun Zhang, Tianyu Zhou, Tetsuya Tsukamoto, Masanobu Oshima, Quan Wang, Xueyuan Cao. The protective effects of 18β-glycyrrhetinic acid against inflammation microenvironment in gastric tumorigenesis targeting PGE2-EP2 receptor-mediated arachidonic acid pathway. European Journal of Inflammation. 2018. 16
大塚旬子, 江澤一生, 安部良, 大島正伸, 大木理恵子. がん抑制遺伝子p53機能喪失を伴った胃がんモデルを用いた胃がんの悪性化機構の解明. 日本癌学会総会記事. 2017. 76回. P-1110

特許 (1件)：

講演・口頭発表等 (37件)：

大腸がん多段階発がんと転移機構
(第113回日本病理学会総会 2024)
Cluster migration and polyclonal metastasis of intestinal tumor cells
(Duke-NUS/NCCS & Kanazawa University CRI Joint Symposium 2024)
Collective migration and polyclonal metastasis mechanism.
(ソウル国際胃がんフォーラム2023 2023)
Organoid experiments to understand the metastasis mechanism.
(第5回韓国国立がんセンターNCC-GCSPインターアカデミーがんシンポジウム 2023)
消化器がん発生と悪性化進展を促進する炎症性微小環境
(第15回 In vivoシンポジウム 2023)

Works (6件)：

Evaluation of combination therapy of docetaxel and aurora kinase inhibitor against gastric cancer
2008 -
Anti-tumor effect of EP4 antagonist against gastric tumorigenesis
2008 -
Evaluation of K19-Nog/C2mE transgenic mice as human gastric cancer model
2007 -
Gene pfofiling analysis using gastric cancer mouse model
2006 -
Cardioprotective effect by gravity-induced COX-2
2005 -

学歴 (4件)：

経歴 (3件)：

委員歴 (2件)：

受賞 (1件)：

所属学会 (7件)：

日本実験動物学会 , 日本生化学会 , 日本分子生物学会 , 日本獣医学会 , 米国癌学会 , 日本癌学会 , American Association of Cancer Research

※　J-GLOBALの研究者情報は、researchmapの登録情報に基づき表示しています。登録・更新については、こちらをご覧ください。

大島 正伸