Analysis of the pathogenesis of diabetic nephropathy
Analysis of physiological and pathophysiological functions of megalin and its related proteins
新規素材ハニカム膜を用いた糸球体上皮細胞培養と同細胞における糖鎖付加酵素の役割
近位尿細管エンドサイトーシスの分子機構と慢性腎臓病の発症機序における病的役割
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論文 (158件):
Sawako Goto, Akihisa Tsutsumi, Yongchan Lee, Michihiro Hosojima, Hideyuki Kabasawa, Koichi Komochi, Satoru Nagatoishi, Kazuya Takemoto, Kouhei Tsumoto, Tomohiro Nishizawa, et al. Cryo-EM structures elucidate the multiligand receptor nature of megalin. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 22. e2318859121
Sawako Goto, Michihiro Hosojima, Hideyuki Kabasawa, Kaho Arai, Kazuya Takemoto, Hiroyuki Aoki, Koichi Komochi, Ryota Kobayashi, Nanako Sugita, Taeko Endo, et al. Megalin-related mechanism of hemolysis-induced acute kidney injury and the therapeutic strategy. The Journal of pathology. 2024
Marcel Bokhove, Takashi Kawamura, Hideo Okumura, Sawako Goto, Yoshiaki Kawano, Stefan Werner, Franziska Jarczowski, Victor Klimyuk, Akihiko Saito, Takashi Kumasaka. The structure of the rat vitamin B12 transporter TC and its complex with glutathionylcobalamin. The Journal of biological chemistry. 2024. 300. 5. 107289-107289
Sawako Goto, Yutaka Yoshida, Michihiro Hosojima, Shoji Kuwahara, Hideyuki Kabasawa, Hiroyuki Aoki, Tomomichi Iida, Ryuhei Sawada, Daisuke Ugamura, Yuta Yoshizawa, et al. Megalin is involved in angiotensinogen-induced, angiotensin II-mediated ERK1/2 signaling to activate Na+-H+ exchanger 3 in proximal tubules. Journal of hypertension. 2023