大根田修

オオネダオサム | OHNEDA Osamu

所属機関・部署：
職名：教授

研究分野 (2件)：発生生物学 , 細胞生物学

競争的資金等の研究課題 (2件)：

2016 - 2018 2型糖尿病由来間葉系幹細胞の単離およびその機能解析
2013 - 2015 ヒト初代培養乳癌幹細胞における浸潤・転移能獲得の分子機能解明

論文 (108件)：

Vuong, Cat-Khanh, Fukushige, Mizuho, Ngo, Nhat-Hoang, Yamashita, Toshiharu, Obata-Yasuoka, Mana, Hamada, Hiromi, Osaka, Motoo, Tsukada, Toru, Hiramatsu, Yuji, Ohneda, Osamu. Extracellular Vesicles Derived from Type 2 Diabetic Mesenchymal Stem Cells Induce Endothelial Mesenchymal Transition under High Glucose Conditions Through the TGFβ/Smad3 Signaling Pathway. Stem cells and development. 2024. 33. 11-12. 262-275
Vuong, Cat-Khanh, Fukushige, Mizuho, Ngo, Nhat-Hoang, Yamashita, Toshiharu, Obata-Yasuoka, Mana, Hamada, Hiromi, Osaka, Motoo, Tsukada, Toru, Hiramatsu, Yuji, Ohneda, Osamu. Extracellular Vesicles Derived from Type 2 Diabetic Mesenchymal Stem Cells Induce Endothelial Mesenchymal Transition under High Glucose Conditions Through the TGFβ/Smad3 Signaling Pathway. Stem cells and development. 2024. 33. 11-12. 262-275
Nguyen, Hoai-Nga Thi, Vuong, Cat-Khanh, Fukushige, Mizuho, Usuda, Momoko, Takagi, Liora Kaho, Yamashita, Toshiharu, Obata-Yasuoka, Mana, Hamada, Hiromi, Osaka, Motoo, et al. Extracellular vesicles derived from SARS-CoV-2 M-protein-induced triple negative breast cancer cells promoted the ability of tissue stem cells supporting cancer progression. FRONTIERS IN ONCOLOGY. 2024. 14
Yamashita, Toshiharu, Vuong, Cat-Khanh, Ngo, Nhat-Hoang, Osaka, Motoo, Hiramatsu, Yuji, Ohneda, Osamu. Impairment of HIF-2α Expression Induced the Compensatory Overexpression of the HIF-1α/SDF-1 Axis to Promote Wound Healing. STEM CELLS AND DEVELOPMENT. 2023. 32. 19-20. 592-605
Fukushige, Mizuho, Ngo, Nhat-Hoang, Lukmanto, Donny, Fukuda, Shinichi, Ohneda, Osamu. Effect of the COVID-19 pandemic on antibiotic consumption: A systematic review comparing 2019 and 2020 data. FRONTIERS IN PUBLIC HEALTH. 2022. 10

講演・口頭発表等 (15件)：

Infant-Modified Adipose-Derived Mesenchymal Stem Cells Modulates Microglial Response in a Rodent Stroke Model
(IEEE 45th Annual International Conference of the Engineering in Medicine and Biology Society (EMBC) 2023)
Extracellular vesicles derived from Wharton’s Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway
(Tsukuba Global Science Week 2022 2022)
Nicotine and SARS-CoV-2 Protein Induce the Malignancy of Lung Cancer Cell. International Student Presentations of Medical and Life Sciences Session.
(Tsukuba Global Science Week 2022 2022)
SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells
(Tsukuba Global Science Week 2022 2022)
Transformed Extracellular Vesicles with High Angiogenic Ability as Therapeutics of Distal Ischemic Tissues
(Tsukuba Global Science Week 2022 2022)

委員歴 (1件)：

- 現在日本生化学会評議委員

受賞 (1件)：

2000 - 日本血液学会奨励賞

所属学会 (7件)：

American Society of Hematology , 日本循環器学会 , 日本再生医療学会 , 日本分子生物学会 , 日本生化学会 , 日本血液学会 , 日本癌学会

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