研究者

J-GLOBAL ID：201401033340438594 更新日: 2024年04月19日

竹馬真理子

Chikuma Mariko

所属機関・部署：
職名：准教授
競争的資金等の研究課題 (4件)：

2021 - 2024 アクアポリン3が制御するがん悪性化の分子機構解明
2016 - 2018 アクアポリンが透過するH2O2による皮膚の炎症形成機構の解明
2012 - 2015 アクアポリン9が炎症性皮膚炎発症に果たすKey Role
2009 - 2011 アクアポリン3の腫瘍形成および細胞増殖への関与と機序解明

論文 (52件)：

By Yukiko Tokifuji, Hodaka Hayabuchi, Takashi Sasaki, Mariko Hara-Chikuma, Keiji Hirota, Hayato Takahashi, Masayuki Amagai, Akihiko Yoshimura, Shunsuke Chikuma. Targeting abatacept-resistant T-helper-17 cells by aldehyde dehydrogenase inhibition. iScience. 2024. 27. 1. 108646-108646
Manami Tanaka, Masato Yasui, Mariko Hara-Chikuma. Aquaporin 3 inhibition suppresses the mitochondrial respiration rate and viability of multiple myeloma cells. Biochemical and biophysical research communications. 2023. 676. 158-164
Manami Tanaka, Anmi Ito, Seiji Shiozawa, Mariko Hara-Chikuma. Anti-tumor effect of aquaporin 3 monoclonal antibody on syngeneic mouse tumor model. Translational Oncology. 2022. 24. 101498-101498
Yundi Shi, Masato Yasui, Mariko Hara-Chikuma. AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression. Biochemistry and Biophysics Reports. 2022. 31. 101317-101317
Kenji Shinohara, Mariko Hara-Chikuma. Low humidity altered the gene expression profile of keratinocytes in a three-dimensional skin model. Molecular Biology Reports. 2022

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MISC (7件)：

Kyoko Nakahigashi, Kenji Kabashima, Akihiko Ikoma, Yoshiki Miyachi, Mariko Hara-Chikuma. AQP3 expression in keratinocytes is involved in hyperplasia in atopic dermatitis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010. 130. S23-S23
M. Hara-Chikuma, S. Chikuma, K. Kabashima, K. Nakahigashi, A. Kamegawa, Y. Fujiyoshi, A. S. Verkman, Y. Sugiyama, S. Inoue, Y. Miyachi. A controlled aquaporin-3 expression in T lymphocytes regulate their migration and trafficking in cutaneous immune reaction. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010. 130. S116-S116
C. Moniaga, M. Chikuma, H. Kawasaki, S. Nakajima, H. Tanizaki, G. Egawa, T. Honda, M. Amagai, Y. Miyachi, K. Kabashima. Flaky tail mouse as a possible model of atopic dermatitis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2009. 129. S56-S56
Catharina Sagita Moniaga, Gyohei Egawa, Hiroshi Kawasaki, Mariko Hara Chikuma, Tetsuya Honda, Hideaki Tanizaki, Saeko Nakajima, Yoshiki Tokura, Yoshiki Miyachi, Masayuki Amagai, et al. FLAKY TAIL MOUSE AS A POSSIBLE MODEL OF ATOPIC DERMATITIS: PRURITUS-ASSOCIATED RESPONSE INDUCED IN FLAKY TAIL MOUSE. ACTA DERMATO-VENEREOLOGICA. 2009. 89. 6. 695-695
Y Sugiyama, Y Ota, M Hara, S Inoue. Gene expression of the water channels, aquaporins, in human keratinocyte and skin-equivalent cultures, and osmotic stress induction of aquaporin-3 mRNA in cultured keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2001. 117. 2. 410-410

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学位 (1件)：

博士(薬学)

経歴 (3件)：

2017/04 - 現在慶應義塾大学医学部准教授
2016/04 - 2017/03 慶應義塾大学医学部専任講師
2011/04 - 2016/03 京都大学医学研究科特定准教授

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