小林稔

Kobayashi Minoru

所属機関・部署：

研究分野 (1件)：細胞生物学

競争的資金等の研究課題 (12件)：

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論文 (39件)：

Gouki Kambe, Minoru Kobayashi, Hiroshi Ishikita, Sho Koyasu, Ester M. Hammond, Hiroshi Harada. ZBTB7A forms a heterodimer with ZBTB2 and inhibits ZBTB2 homodimerization required for full activation of HIF-1. Biochemical and Biophysical Research Communications. 2024. 733. 150604-150604
Huiying Mu, Shuai Shao, Bingquan Wu, Koji Miki, Minoru Kobayashi, Hiroshi Harada, Kouichi Ohe. Fast tumor imaging using pH-responsive aggregation of cyanine dyes with rapid clearance. Sensors and Actuators B: Chemical. 2024. 413. 135876-135876
Iori Tamura, Daichi M. Sakamoto, Bo Yi, Yutaro Saito, Naoki Yamada, Jumpei Morimoto, Yoichi Takakusagi, Masafumi Kuroda, Shimpei I. Kubota, Hiroyuki Yatabe, et al. Click3D: Click reaction across deep tissues for whole-organ 3D fluorescence imaging. Science Advances. 2024. 10. 29
Lee PWT, Suwa T, Kobayashi M, Yang H, Koseki LR, Takeuchi S, Chow CCT, Takaaki Yasuhara, Hiroshi Harada. Hypoxia- and Postirradiation reoxygenation-induced HMHA1/ARHGAP45 expression contributes to cancer cell invasion in a HIF-dependent manner. British journal of cancer. 2024
Peter W.T. LEE, Lina Rochelle Koseki, Takao Haitani, Hiroshi Harada, Minoru Kobayashi. Hypoxia-Inducible Factor-Dependent and Independent Mechanisms Underlying Chemoresistance of Hypoxic Cancer Cells. Cancers. 2024

MISC (9件)：

小林稔, 平岡, 真寛, 原田浩. 時計遺伝子PER2と低酸素応答機構の相互作用メカニズムの解析. 2014
Minoru Kobayashi, Hiroshi Harada. [Hypoxic stress and HIF]. Seikagaku. The Journal of Japanese Biochemical Society. 2013. 85. 3. 187-195
小林稔, 曽麗華, 後藤容子, 井上実, 板坂聡, 吉村通央, 原田浩, 平岡真寛. IDH3はHIF-1alphaを安定化して腫瘍増殖を亢進する. 2013
小林稔, 脇田大功, 岩淵禎弘, 佐藤崇之, 北村, 秀光, 西村孝司. Method for establishment of cancer stem-like cells by introduction of oncogenes into mesenchymal stem cells. 2013
Establishment of airway smooth muscle cell line useful for evaluating neuro-immuno cross-talk in Th1-mediated airway inflammation. 2011

講演・口頭発表等 (22件)：

Decreased expression levels of a histone acetyl reader, ATAD2, induces chemoresistance of cancer cells under severe hypoxia by inhibiting cell cycle progression in S phase
(第18回がんとハイポキシア研究会 2022)
DNA double strand breaksのインビボ定量評価に向けたEGFP-53BP1ノックインマウスの樹立
(第62回日本放射線影響学会 2019)
A Circadian Clock Gene, PER2, Activates HIF-1 as an Effector Molecule for Recruitment of HIF-1α to Promoter Regions of Its Downstream Genes
(第34回放生研国際シンポジウム 2018)
HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating Shh.
(第77回日本癌学会学術総会 2018)
A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of Its downstream genes
(The 17th International Joint Mini-Symposium on Molecular and Cell Biology 2018)

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小林 稔