蘇美慈

ソミジ | TZU SU MEI

所属機関・部署：
職名：助教

研究分野 (3件)：腫瘍生物学 , ウイルス学 , 免疫学

研究キーワード (4件)：自己免疫 , 免疫シグナル伝達 , 免疫制御・移植免疫 , 免疫監視・腫瘍免疫

競争的資金等の研究課題 (2件)：

2022 - 2025 A novel mechanism of fibronectin/LILRB4 immune checkpoint in the regulation of the tumor microenvironment
2019 - 2022 The role of LILRB4 on MDSC-mediated immunosuppression in tumor environment

論文 (18件)：

Fumika Itagaki, Keita Nakatsuka, Haruka Sakai, Shota Endo, Mei-Tzu Su, Toshiyuki Takai. Fibronectin on target cells attenuates natural cytotoxicity of NK cells via myeloid immune checkpoint ILT3/LILRB4/gp49B. International Immunology. 2023. 35. 7. 339-348
Shotaro Miyamoto, Takumi Chiba, So Itoi, Mei-Tzu Su, Toshiyuki Takai. LILRB4/gp49B Co-Localizes with Integrin via Fibronectin at Focal Adhesion Sites on Mast Cells. The Tohoku Journal of Experimental Medicine. 2023. 259. 4. 273-284
Mei-Tzu Su, Karin Ono, Dai Kezuka, Shotaro Miyamoto, Yu Mori, Toshiyuki Takai. Fibronectin-LILRB4/gp49B interaction negatively regulates osteoclastogenesis through inhibition of RANKL-induced TRAF6/TAK1/NF-kB/MAPK signaling. International immunology. 2022
So Itoi, Naoyuki Takahashi, Haruka Saito, Yusuke Miyata, Mei-Tzu Su, Dai Kezuka, Fumika Itagaki, Shota Endo, Hiroshi Fujii, Hideo Harigae, et al. Myeloid immune checkpoint ILT3/LILRB4/gp49B can co-tether fibronectin with integrin on macrophages. International immunology. 2022. 34. 8. 435-444
Naoyuki Takahashi, So Itoi, Mei-Tzu Su, Shota Endo, Toshiyuki Takai. Co-localization of Fibronectin Receptors LILRB4/gp49B and Integrin on Dendritic Cell Surface. The Tohoku Journal of Experimental Medicine. 2022. 257. 3. 171-180

MISC (2件)：

学歴 (1件)：

経歴 (3件)：

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蘇 美慈