研究者
J-GLOBAL ID：201801011639497674   更新日: 2024年04月01日

HAYES CLAIR NELSON

ヘイズ クレアーネルソン | HAYES CLAIR NELSON
所属機関・部署：
広島大学

広島大学 について


研究キーワード (7件)： データベース ,  スーパーコンピュータ ,  次世代シーケンシング ,  ジャヴァ ,  肝臓 ,  ウイルス学 ,  肝炎
競争的資金等の研究課題 (1件)：
  • 2012 - 2013 次世代シーケンサーを用いたHCVに対する3者併用療法中の耐性株の動態の解析
論文 (139件)：
  • Uchida, Takuro, Imamura, Michio, Hayes, C. Nelson, Suehiro, Yosuke, Teraoka, Yuji, Ohya, Kazuki, Aikata, Hiroshi, Abe-Chayama, Hiromi, Ishida, Yuji, Tateno, Chise, et al. HBV with precore and basal core promoter mutations exhibits a high replication phenotype and causes ER stress-mediated cell death in humanized liver chimeric mice. HEPATOLOGY. 2023. 78. 3. 929-942
  • Makokha, Grace Naswa, Chayama, Kazuaki, Hayes, C. Nelson, Abe-Chayama, Hiromi, Abuduwaili, Maidina, Makoto, Hijikata. Deficiency of SCAP inhibits HBV pathogenesis via activation of the interferon signaling pathway. VIROLOGY. 2023. 585. 248-258
  • Johira, Yusuke, Nakahara, Takashi, Kinami, Takahiro, Yamasaki, Shintaro, Kosaka, Masanari, Shirane, Yuki, Miura, Ryoichi, Murakami, Serami, Yano, Shigeki, Amioka, Kei, et al. Impact and usefulness of the transition to the new MAFLD classification for non-B, non-C HCC: a retrospective cohort study. BMC GASTROENTEROLOGY. 2023. 23. 1
  • Suehiro, Yosuke, Tsuge, Masataka, Kurihara, Mio, Uchida, Takuro, Fujino, Hatsue, Ono, Atsushi, Yamauchi, Masami, Makokha, Grace Naswa, Nakahara, Takashi, Murakami, Eisuke, et al. Hepatitis B Virus (HBV) Upregulates TRAIL-R3 Expression in Hepatocytes Resulting in Escape From Both Cell Apoptosis and Suppression of HBV Replication by TRAIL. JOURNAL OF INFECTIOUS DISEASES. 2023. 227. 5. 686-695
  • Uchida, Takuro, Teraoka, Yuji, Imamura, Michio, Abe-Chayama, Hiromi, Makokha, Grace Naswa, Hayes, Clair Nelson, Aikata, Hiroshi, Hamamura, Satoko, Ishida, Yuji, Tateno, Chise, et al. A novel cDNA-uPA/SCID/Rag2(-/-)/Jak3(-/-) mouse model for hepatitis virus infection and reconstruction of human immune system. JOURNAL OF VIRAL HEPATITIS. 2023. 30. 3. 262-272
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書籍 (1件)：
  • Hepatocellular Carcinoma
    Codon Publications 2019
講演・口頭発表等 (15件)：
  • Transcriptomic and metabolomic analysis of growth hormone response in a fatty liver model using human hepatocyte chimeric mice
    (Liver Meeting 2022)
  • Prediction of hepatitis B virus co-receptors using semi-supervised learning
    (AASLSD conference 2019 2019)
  • Estimating HBV gene expression levels based on RNAseq data in a human hepatocyte chimeric mouse mode
    (高効率感染細胞系と長期持続肝炎マウスモデルを用いたHBV排除への創薬研究 2017)
  • Characterizing the early immune response to hepatitis B virus infection using the human hepatocyte chimeric mouse model
    (AASLD 2017)
  • Hepatitis B virus infection leads to activation of interferon-stimulated genes in primary cultured human hepatocytes, but infection efficiency decreases monotonically with decreasing cell density
    (HBV Single topic conference 2014 2014)
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受賞 (7件)：
  • 2019/11/09 - American Association for the Study of Liver Diseases Presidential poster of distinction
  • 2009/12/16 - Genome Informatics Workshop Best paper award
  • 2006/04/01 - 日本学術振興会 日本学術振興会研究員
  • 2002/05/15 - Pennsylvania State University Graduate Assistant Outstanding Teaching Award
  • 1999/08/01 - Pennsylvania State University J. Ben and Helen D. Hill graduate student award
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