2017 - 2018 抗がん剤の開発を目指したグルタチオン S トランスフェラーゼの共有結合性阻害剤の開発
2011 - 2016 MEMSを利用した細胞の3次元組織構築
2014 - 2016 バクテリア内膜を固定したデバイスによるトランスロコン解析
2013 - 2014 トランスポーター解析デバイスの開発とヌクレオシド取り込み系の解明
全件表示
論文 (36件):
Yuki Yoshida, Yushi Niimi, Daichi Fushihara, Hideo Katakura, Ryusuke Fukui, Hirotaka Murase, Fumiaki Tomoike, Fumitaka Hashiya, Tsutomu Murakami, Eiichi N. Kodama, et al. 2′-β-Methylselenyl nucleos(t)ide analogs as reverse transcriptase inhibitors against diverse HIV mutants. Bioorganic & Medicinal Chemistry. 2024. 110. 117813-117813
Fangjie Lyu, Takashi Tomita, Naoko Abe, Haruka Hiraoka, Fumitaka Hashiya, Yuko Nakashima, Shiryu Kajihara, Fumiaki Tomoike, Zhaoma Shu, Kazumitsu Onizuka, et al. Topological capture of mRNA for silencing gene expression. Chemical communications (Cambridge, England). 2023. 59. 77. 11564-11567
Tetsuji Okada, Fumiaki Tomoike. Distance-based global analysis of consistent cis-bonds in protein backbones. Heliyon. 2023. 9. 8. e18598-e18598
Yoshida, Y, Zheng, T, Tanabe, W, Tomoike, F, Hashiya, F, Suzuki, T, Hirota, S, Saiki, Y, Horii, A, Hirayama, A, et al. Development of Fluorophosphoramidate as a Biocompatibly Transformable Functional Group and its Application as a Phosphate Prodrug for Nucleoside Analogs. ChemMedChem. 2022. online. 17. e202200188
Kazuki Yamaoka, Ryota Oikawa, Naoko Abe, Kosuke Nakamoto, Fumiaki Tomoike, Fumitaka Hashiya, Yasuaki Kimura, Hiroshi Abe. Complete chemical synthesis of long DNA transcriptable in human cells. ChemBioChem. 2021
Shishido Yuko, Tomoike Fumiaki, Kimura Yasuaki, Kuwata Keiko, Yano Takato, Fukui Kenji, Fujikawa Haruka, Sekido Yoshitaka, Murakami-Tonami Yuko, Kameda Tomoshi, et al. Development of glutathione S-transferase (GST) covalent inhibitor. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2018. 255. .