志見剛

シミタケシ | Shimi Takeshi

所属機関・部署：
職名：特任准教授

研究分野 (1件)：細胞生物学

研究キーワード (3件)：細胞核の構造と機能 , 蛍光顕微鏡 , 細胞生物学

競争的資金等の研究課題 (5件)：

論文 (45件)：

Yohei Kono, Takeshi Shimi. Crosstalk between mitotic reassembly and repair of the nuclear envelope. Nucleus. 2024
洋平河野, 剛志見. ラミノパチーにおける核膜の修復異常. 生化学. 2024. 96. 1. 101-105
Yohei Kono, Chan-Gi Pack, Takehiko Ichikawa, Arata Komatsubara, Stephen A. Adam, Keisuke Miyazawa, Loïc Rolas, Sussan Nourshargh, Ohad Medalia, Robert D. Goldman, et al. Delayed localization of A-type lamins to the rupture sites in Hutchinson-Gilford progeria syndrome. bioRxiv. 2023
Kei Fukuda, Takeshi Shimi, Chikako Shimura, Takao Ono, Takehiro Suzuki, Kenta Onoue, Satoko Okayama, Hisashi Miura, Ichiro Hiratani, Kazuho Ikeda, et al. Epigenetic plasticity safeguards heterochromatin configuration in mammals. Nucleic Acids Research. 2023. 51. 12. 6190-6207
Shimi Takeshi, Kono Yohei, Adam Stephen, Sato Yuko, Reddy Karen, Zheng Yixian, Medalia Ohad, Goldman Robert, Kimura Hiroshi. 核膜研究の最前線ラミノパチーにおいて核膜の修復異常を引き起こす分子機構の解明(Hot topics on nuclear envelope Molecular mechanisms underlying defective repair of nuclear envelope ruptures in laminopathies). The Journal of Physiological Sciences. 2023. 73. Suppl.1. 43-43

MISC (62件)：

Mohammad Mubarak Hosain, Yohei Kono, Keisuke Miyazawa, Takehiko Ichikawa, Takeshi Shimi, Takeshi Fukuma. Nanoendoscopy-AFM: A Novel Technique for Intracellular Imaging and Measurement of Mechanical Properties. 2024 Materials Research Society (MRS) Fall Meeting & Exhibit. 2024
川瀬雅貴, 河野洋平, 市川壮彦, 木村宏, 福間剛士, 眞貝洋一, 志見剛. 細胞核の力学的特性はヘテロクロマチン構造によって強化される. 日本遺伝学会第96回大会. 2024. O3-4
河野洋平, 丹羽達也, 郑诣先, Adam Stephen, Goldman Rober, 木村宏, 志見剛. 核ラミンを全て欠損したマウス胎児線維芽細胞株の樹立と解析. 日本細胞生物学会大会講演要旨集 76回. 2024. 3P20
Alexis S. Borowiak, T. Ichikawa, M. Itou, T. Shimi, Y. Kono, R. Nitta, T. Fukuma. Mechanical properties of hiPSC derived-cardiomyocytes: investigating beating and non-beating cell’s nucleus via Nanoendoscopy-AFM. 21st International Union of Pure and Applied Biophysics and 62nd Biophysics Society of Japan (IUPAB-BSJ 2024). 2024. 26P-252
A. S. Borowiak, K. Sivashanmugan, T. Ichikawa, E. Hirata, T. Shimi, Y. Kono, T. Fukuma. New approaches to directly image the surface of the nucleus at nanometer scale. European Materials Research Society (E-MRS) 2024 Spring Meeting. 2024

特許 (4件)：

講演・口頭発表等 (7件)：

New insights into the structure of the nuclear lamina revealed by nanoscale resolution microscopy
(Cold Spring Harbor Meeting Nuclear Organization and Function 2014)
Three-dimensional structure and organization of the nuclear lamina revealed by nanoscale resolution microscopy
(The 4D Nucleome 2014)
Loss of nuclear lamin B1 is required for chromatin remodeling during cellular senescence
(Molecular Biology Society of Japan Annual Meeting 2013)
The nuclear lamin networks: defining the chromatin landscape
(Symposium: chromatin structure dynamics and functions 2013)
The roles of nuclear lamin B1 in poliferation, longevity and senescence
(American Society for Cell Biology 51st Annual Meeting 2011)

学位 (1件)：

経歴 (8件)：

2023/07 - 現在金沢大学ナノ生命科学研究所特任准教授
2018/04 - 2023/05 東京工業大学科学技術創成研究院科学技術創成研究院細胞制御工学研究センター特任准教授
2017/08 - 2019/03 Northwestern University, Feinberg School of Medicine Department of Cell and Molecular Biology 助教
2016/05 - 2017/07 Northwestern University, Feinberg School of Medicine Department of Biochemistry and Molecular Genetics 助教
2015/06 - 2016/04 University of Chicago Department of Human Genetics 上級研究員

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志見 剛