研究者
J-GLOBAL ID:201901010462583487   更新日: 2024年03月06日

プップリン レオナルド

Leonardo Puppulin
所属機関・部署:
研究分野 (4件): ナノ材料科学 ,  生物物理学 ,  生体材料学 ,  生体医工学
競争的資金等の研究課題 (3件):
  • 2019 - 2022 Nanometer scale resolution imaging of pH and reactive oxygen species on the outer membrane surface for fast and effective cell discrimination in cancer tissues.
  • 2016 - 2019 光学的方法を用いた組織間質液イオン環境の非侵襲的測定法開発
  • 2011 - 2012 人工関節用の生体材料における顕微ラマン光分析の開発
論文 (44件):
  • Shotaro Tsujioka, Ayumi Sumino, Yutaro Nagasawa, Takashi Sumikama, Holger Flechsig, Leonardo Puppulin, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, et al. Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy. Science advances. 2023. 9. 26. eadh1069
  • Leonardo Puppulin, Junichiro Ishikawa, Ayumi Sumino, Arin Marchesi, Holger Flechsig, Kenichi Umeda, Noriyuki Kodera, Hiroshi Nishimasu, Mikihiro Shibata. Dynamics of Target DNA Binding and Cleavage by Staphylococcus aureus Cas9 as Revealed by High-Speed Atomic Force Microscopy. ACS Nano. 2023
  • Shin Morioka, Shoko Sato, Naoki Horikoshi, Tomoya Kujirai, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, Leonardo Puppulin, Ayumi Sumino, et al. High-Speed Atomic Force Microscopy Reveals Spontaneous Nucleosome Sliding of H2A.Z at the Subsecond Time Scale. Nano letters. 2023. 23. 5. 1696-1704
  • Ayumi Sumino, Yimeng Zhao, Daichi Mukai, Takashi Sumikama, Leonardo Puppulin, Motoyuki Hattori, Mikihiro Shibata. Antithetic effects of agonists and antagonists on the structural fluctuations of TRPV1 channel. 2023
  • Shotaro Tsujioka, Ayumi Sumino, Yutaro Nagasawa, Takashi Sumikama, Holger Flechsig, Leonardo Puppulin, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, et al. Evolutionarily acquired activity-dependent transformation of the CaMKII holoenzyme. 2023
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MISC (2件):
  • Ayumi Sumino, Takashi Sumikama, Leonardo Puppulin, Mikihiro Shibata, Katsumasa Irie. Dissociation and inter-channel dimerization of voltage-sensor domains (VSD) of voltage-gated Na+ channel in the resting state. The Journal of Physiological Sciences. 2023. 73. 95
  • 川越 裕介, 射場 大輔, 中村 守正, プップリン レオナルド, ペッッオティ ジュセッペ, 森脇 一郎. S111023 ラマン分光分析のためのプラスチック歯車用小型曲げ疲労試験機の開発([S111-02]第19回卒業研究コンテスト(2)). 年次大会 : Mechanical Engineering Congress, Japan. 2013. 2013. "S111023-1"-"S111023-5"
講演・口頭発表等 (3件):
  • Exploring the potential of HS-AFM for simultaneous topography and molecular recognition imaging
    (NanoLSI Open Seminar 2022)
  • Surface enhanced Raman spectroscopy probe for nanometer-scale measurement of pH and hydrogen peroxides on the outer membrane of cells
    (The 97th Annual Meeting of the Physiological Society of Japan 2020)
  • Highly localized pH sensing on the outer membrane of cells using surface enhanced Raman spectroscopy
    (FAOPS congress in conjunction with the 96th annual meeting of physiological society of Japan 2019)
経歴 (4件):
  • 2019/03 - 現在 金沢大学 WPI ナノ生命科学研究所 Assistant professor
  • 2013/09 - 2019/02 京都府立医科大学 Postdoctoral researcher
  • 2011/09 - 2013/08 京都工芸繊維大学 JSPS Post-doc fellow
  • 2006/05 - 2007/09 CNR Italian Council of National Research Institute of Science and Technology for Ceramic materials (ISTEC/CNR) Researcher
所属学会 (1件):
日本生理学会
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