2018 - 2020 Target determination and exploratory research for discovery of new drugs against Chagas disease
2016 - 2018 寄生原虫トリパノソーマに対する創薬標的の探索
2009 - 2010 Predoctoral Fellowship
全件表示
論文 (19件):
Yancheng Liu, Yuko Takagi, Milyadi Sugijanto, Kieu Duong My Nguyen, Akira Hirata, Hiroyuki Hori, C. Kiong Ho. Genetic and Functional Analyses of Archaeal ATP-Dependent RNA Ligase in C/D Box sRNA Circularization and Ribosomal RNA Processing. Frontiers in Molecular Biosciences. 2022. 9
Yuko Takagi, Mari Sato, Masami Naya, Chikara Sato. Differentiating Trypanosoma cruzi in a Host Mammalian Cell Imaged in Aqueous Liquid by Atmospheric Scanning Electron Microscopy. Microbiology spectrum. 2022. e0141321
Yuko Takagi, Naoyuki Kuwabara, Truong Tat Dang, Koji Furukawa, C. Kiong Ho. Crystal structures of the RNA triphosphatase from Trypanosoma cruzi provide insights into how it recognizes the 5′-end of the RNA substrate. Journal of Biological Chemistry. 2020. 295. 27. 9076-9086
Yukie Akutsu, Motomichi Doi, Koji Furukawa, Yuko Takagi. Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System. Journal of Visualized Experiments. 2019. 149
Yuko Takagi, Yukie Akutsu, Motomichi Doi, Koji Furukawa. Utilization of proliferable extracellular amastigotes for transient gene expression, drug sensitivity assay, and CRISPR/Cas9-mediated gene knockout in Trypanosoma cruzi. PLOS Neglected Tropical Diseases. 2019. 13. 1