仁平(平) 直江

ニヒラ(タイラ) ナオエ | Taira Nihira Naoe

所属機関・部署：
職名：特任講師

研究キーワード (5件)： PD-L1 , Post-translational modification , Immune checkpoint , DNA damage response , p53

競争的資金等の研究課題 (15件)：

全件表示

論文 (20件)：

Naoe Taira Nihira, Tomohiko Ohta, Zichuan Liu, Xiangpeng Dai. Editorial: Community series in post-translational modifications of proteins in cancer immunity and immunotherapy, volume II. Frontiers in immunology. 2023. 14. 1289016-1289016
Jing Zhu, Wenwen Wu, Yukiko Togashi, Naoe Taira Nihira, Yoshikazu Johmura, Dajiang Zhu, Makoto Nakanishi, Yasuo Miyoshi, Tomohiko Ohta. Alteration of Trop-2 expression in breast cancer cells by clinically used therapeutic agents and acquired tamoxifen resistance. Breast cancer (Tokyo, Japan). 2022. 29. 6. 1076-1087
[筆頭共著] Yang Gao, Naoe Taira Nihira, Xia Bu, Chen Chu, Jinfang Zhang, Aleksandra Kolodziejczyk, Yizeng Fan, Ngai Ting Chan, Leina Ma, Jing Liu, et al. Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy. Nature cell biology. 2020. 22. 9. 1064-1075
Nikita Patel, Juehong Wang, Kumiko Shiozawa, Kevin B Jones, Yanfeng Zhang, Jeremy W Prokop, George G Davenport, Naoe T Nihira, Zhenyue Hao, Derek Wong, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. iScience. 2019. 13. 43-54
Emilie Clement, Hiroyuki Inuzuka, Naoe T Nihira, Wenyi Wei, Alex Toker. Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors. Science signaling. 2018. 11. 521

MISC (4件)：

Naoe Taira Nihira, Yoshio Miki. Regulation of Intrinsic Functions of PD-L1 by Post-Translational Modification in Tumors. Frontiers in oncology. 2022. 12. 825284-825284
Kouhei Shimizu, Naoe Taira Nihira, Hiroyuki Inuzuka, Wenyi Wei. Physiological functions of FBW7 in cancer and metabolism. Cellular signalling. 2018. 46. 15-22
Naoe Taira Nihira, Kiyotsugu Yoshida. Engagement of DYRK2 in proper control for cell division. Cell cycle (Georgetown, Tex.). 2015. 14. 6. 802-7
N Taira, K Yoshida. Post-translational modifications of p53 tumor suppressor: determinants of its functional targets. Histology and histopathology. 2012. 27. 4. 437-43

学位 (1件)：

経歴 (10件)：

2022/11 - 現在聖マリアンナ医科大学応用分子腫瘍学特任講師
2020/04 - 独立行政法人日本学術振興会特別研究員
2018/04 - 2020/03 東北大学歯学研究科小児発達歯科学分野非常勤講師
2015/09 - 2018/03 Beth Israel Deaconess Medical Center, Harvard Medical School Instructor
2015/04 - 2017/03 独立行政法人日本学術振興会海外特別研究員

全件表示

受賞 (5件)：

所属学会 (4件)：

日本乳癌学会 , 日本生化学会 , アメリカ癌学会 , 日本癌学会

※　J-GLOBALの研究者情報は、researchmapの登録情報に基づき表示しています。登録・更新については、こちらをご覧ください。