2020 - 2023 Cell-type-specific proteome profiling of cortical GABAergic interneurons in monogenic mouse models of autism spectrum disorders
2014 - 2016 自閉症関連遺伝子欠損による神経活動依存的な翻訳異常のプロテオミクス解析
2011 - 2013 精神疾患における凝集性タンパク質の構造機能解析
論文 (20件):
Kelvin K. Hui, Shinya Yamanaka. iPS cell therapy 2.0: Preparing for next-generation regenerative medicine. BioEssays. 2024
Josephine W Thinwa, Zhongju Zou, Emily Parks, Salwa Sebti, Kelvin Hui, Yongjie Wei, Mohammad Goodarzi, Vibha Singh, Greg Urquhart, Jenna L Jewell, et al. CDKL5 regulates p62-mediated selective autophagy and confers protection against neurotropic viruses. The Journal of clinical investigation. 2024. 134. 1
Ryo Endo, Yi-Kai Chen, John Burke, Noriko Takashima, Nayan Suryawanshi, Kelvin K Hui, Tatsuhiko Miyazaki, Motomasa Tanaka. Dysregulation of ribosome-associated quality control elicits cognitive disorders via overaccumulation of TTC3. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 12. e2211522120
Kelvin K Hui, Maya Latif, Chesa Dojo Soeandy, Shudi Huang, Christopher E Rodgers, Andrew J Elia, Jeffrey T Henderson. Cisplatin toxicity in the developing brain displays an absolute requirement for caspase-3. Experimental neurology. 2022. 351. 114010-114010
Kelvin K Hui, Ryo Endo, Akira Sawa, Motomasa Tanaka. A Perspective on the Potential Involvement of Impaired Proteostasis in Neuropsychiatric Disorders. Biological psychiatry. 2022. 91. 4. 335-345
2003 - 2010 University of Toronto Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy Doctorate of Philosophy (PhD), Pharmaceutical Sciences and Collaborative Program in Neuroscience
1999 - 2003 University of Toronto Department of Pharmacology, Faculty of Arts and Science Honours Bachelor of Science (HBSc), Pharmacology and Toxicology Double Specialist
経歴 (3件):
2020/11 - 2022/08 Albert Einstein College of Medicine Department of Developmental and Molecular Biology
2020/01 - 2020/10 University of Texas Southwestern Medical Center/Howard Hughes Medical Institute Center for Autophagy Research, Department of Internal Medicine
2011/02 - 2019/12 RIKEN Brain Science Institute/Center for Brain Science Laboratory for Protein Conformation Diseases
所属学会 (5件):
International Society for Stem Cell Research
, International Behavioral Neuroscience Society
, Canadian Association for Neuroscience
, 日本神経科学学会
, Society for Neuroscience