研究者
J-GLOBAL ID:202301016591134495
更新日: 2024年11月02日
江原 晴彦
Ehara Haruhiko | Ehara Haruhiko
所属機関・部署:
職名:
上級研究員
競争的資金等の研究課題 (3件):
- 2020 - 2025 転写と共役したヌクレオソーム再構築の分子メカニズムの解明
- 2018 - 2021 クライオ電子顕微鏡を用いた転写伸長超複合体の構造解析
- 2009 - 2011 真核生物のRNAポリメラーゼにおける転写開始/終結機構の分子的基盤の解明
論文 (30件):
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Masahiro Shimizu, Hiroki Tanaka, Masahiro Nishimura, Nobuhiro Sato, Kayo Nozawa, Haruhiko Ehara, Shun-ichi Sekine, Ken Morishima, Rintaro Inoue, Yoshimasa Takizawa, et al. Asymmetric fluctuation of overlapping dinucleosome studied by cryo-electron microscopy and small-angle X-ray scattering. PNAS Nexus. 2024
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Tatsuo Yanagisawa, Yuko Murayama, Haruhiko Ehara, Mie Goto, Mari Aoki, Shun-Ichi Sekine. Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nature communications. 2024. 15. 1. 7854-7854
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Tomoaki Kimura, Seiya Hirai, Tomoya Kujirai, Risa Fujita, Mitsuo Ogasawara, Haruhiko Ehara, Shun-Ichi Sekine, Yoshimasa Takizawa, Hitoshi Kurumizaka. Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K. Genes to cells : devoted to molecular & cellular mechanisms. 2024
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Heeyoun Bunch, Deukyeong Kim, Masahiro Naganuma, Reiko Nakagawa, Anh Cong, Jaehyeon Jeong, Haruhiko Ehara, Hongha Vu, Jeong Ho Chang, Matthew J Schellenberg, et al. ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nature communications. 2023. 14. 1. 8341-8341
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Munetaka Akatsu, Haruhiko Ehara, Tomoya Kujirai, Risa Fujita, Tomoko Ito, Ken Osumi, Mitsuo Ogasawara, Yoshimasa Takizawa, Shun-Ichi Sekine, Hitoshi Kurumizaka. Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA. The Journal of biological chemistry. 2023. 299. 12. 105477-105477
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