リンジェイソン

リンジェイソン | LIN JASON

所属機関・部署：
職名：研究員
競争的資金等の研究課題 (6件)：

2023 - 2027 新世代in situ hybridization法の確立と多形肉腫の進化過程の解明
2021 - 2025 深層学習による人工エピゲノム操作因子におけるゲノム干渉効果の評価及び予測
2021 - 2024 変異mtDNA標的薬剤による変異ミトコンドリア除去治療法開発
2020 - 2022 がん特異的ゲノム変異を標的にした薬剤候補化合物の開発
2020 - 2021 Design, development and validation of ultra-sensitive detection platform for rare somatic genomic aberrations

全件表示

論文 (30件)：

Jihang Yao, Keizo Takenaga, Nobuko Koshikawa, Yuki Kida, Jason Lin, Takayoshi Watanabe, Yoshiaki Maru, Yoshitaka Hippo, Seigi Yamamoto, Yuyan Zhu, et al. Anticancer effect of a pyrrole-imidazole polyamide-triphenylphosphonium conjugate selectively targeting a common mitochondrial DNA cancer risk variant in cervical cancer cells. International Journal of Cancer. 2023. 152. 5. 962-976
Jason Lin, Shang-Chuen Wu. Implications of Transglutaminase-Mediated Protein Serotonylation in the Epigenetic Landscape, Small Cell Lung Cancer, and Beyond. Cancers. 2023. 15. 4. 1332-1332
Akiko Tsujimoto, Niina Matsuo, Xiaoyi Lai, Takahiro Inoue, Hiroyuki Yoda, Jason Lin, Yoshinao Shinozaki, Takayoshi Watanabe, Nobuko Koshikawa, Atsushi Takatori, et al. Use of DNA-alkylating pyrrole-imidazole polyamides for anti-cancer drug sensitivity screening in pancreatic ductal adenocarcinoma. Cancer Medicine. 2022. 12. 5. 5821-5832
Takao Morinaga, Takashi Inozume, Masahito Kawazu, Youki Ueda, Nicolas Sax, Kazuo Yamashita, Shusuke Kawashima, Joji Nagasaki, Toshihide Ueno, Jason Lin, et al. Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration. Cancer Research Communications. 2022. 2. 7. 739-753
Yosuke Iwatate, Hajime Yokota, Isamu Hoshino, Fumitaka Ishige, Naoki Kuwayama, Makiko Itami, Yasukuni Mori, Satoshi Chiba, Hidehito Arimitsu, Hiroo Yanagibashi, et al. Transcriptomic analysis reveals high ITGB1 expression as a predictor for poor prognosis of pancreatic cancer. PLOS ONE. 2022. 17. 6. e0268630-e0268630

MISC (1件)：

Hiroki Nagase, Kiriko Hiraoka, Takahiro Inoue, Hiroyuki Yoda, Krishnamurthy Sakthisri, Jason Lin, Takayoshi Watanabe, Nobuko Koshikawa, Atsushi Takatori. Mutated cancer cell-specific cell death activity of alkylating Pyrrole-Imidazole polyamide conjugates targeting a variety of oncogenic driver gene mutations. CANCER RESEARCH. 2016. 76

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