研究者
J-GLOBAL ID:202401007118725999
更新日: 2024年10月02日
矢島 広大
ヤジマ コウダイ | Kodai Yajima
所属機関・部署:
職名:
助教
研究キーワード (1件):
トランスポーター、抗体医薬品
競争的資金等の研究課題 (1件):
- 2024 - 2026 薬物構造の理解から抗体医薬品の免疫原性要因を探求する
論文 (6件):
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Yajima K, Akiyoshi T, Sakamoto K, Suzuki Y, Oka T, Imaoka A, Yamamura H, Kurokawa J, Ohtani H. Determination of single-molecule transport activity of OATP2B1 by measuring the number of transporter molecules using electrophysiological approach. Journal of Pharmacological Sciences. 2023. 153. 3. 153-160
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Han H, Akiyoshi T, Morita T, Tsuchitani T, Nabeta M, Yajima K, Imaoka A, Ohtani H. The Effects of Jabara Juice on the Intestinal Permeation of Fexofenadine. Biological and Pharmaceutical Bulletin. 2023. 46. 12. 1745-1752
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Han H, Akiyoshi T, Morita T, Kataoka H, Katayama K, Yajima K, Imaoka A, Ohtani H. Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants. Drug Metabolism and Pharmacokinetics. 2022. 47
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Araki N, Morita T, Akiyoshi T, Kataoka H, Yajima K, Katayama K, Imaoka A, Ohtani H. Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants. Drug Metabolism and Pharmacokinetics. 2022. 46
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Morita T, Akiyoshi T, Tsuchitani T, Kataoka H, Araki N, Yajima K, Katayama K, Imaoka A, Ohtani H. Inhibitory Effects of Cranberry Juice and Its Components on Intestinal OATP1A2 and OATP2B1: Identification of Avicularin as a Novel Inhibitor. Journal of Agricultural and Food Chemistry. 2022. 70. 10. 3310-3320
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MISC (2件):
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Citrus Fruit-Derived Flavanone Glycoside Narirutin is a Novel Potent Inhibitor of Organic Anion-Transporting Polypeptides. Journal of Agricultural and Food Chemistry. 2020
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Tokio Morita, Takeshi Akiyoshi, Ryo Sato, Kazuhiro Katayama, Kodai Yajima, Hiroki Kataoka, Ayuko Imaoka, Yoshikazu Sugimoto, Hisakazu Ohtani. pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2. Drug Metabolism and Pharmacokinetics. 2020. 35. 2. 220-227
学歴 (2件):
- 2019 - 2024 慶應義塾大学大学院 薬学研究科 薬学専攻
- 2012 - 2018 慶應義塾大学 薬学部 薬学科
学位 (1件):
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